Thermostable proteins: structural stability and design
"Thermostable Proteins: Structural Stability and Design provides a comprehensive, updated account of the physical basis of enhanced stability of thermophilic proteins and the design of tailor-made thermostable proteins, paving the way for their possible industrial applications. This book is dev...
Gespeichert in:
| Weitere beteiligte Personen: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | Englisch |
| Veröffentlicht: |
Boca Raton, Fla.
CRC Press
2012
|
| Schlagwörter: | |
| Links: | https://learning.oreilly.com/library/view/-/9781439839140/?ar |
| Zusammenfassung: | "Thermostable Proteins: Structural Stability and Design provides a comprehensive, updated account of the physical basis of enhanced stability of thermophilic proteins and the design of tailor-made thermostable proteins, paving the way for their possible industrial applications. This book is devoted to understanding the survival mechanisms of "thermophilic life forms" at the molecular level with an emphasis on design strategies. The review chapters presented in Thermostable Proteins span a wide range of protein thermostability research. Basic structural, thermodynamic, and kinetic principles are explained and molecular strategies for the adaptation to high temperatures are delineated. In addition, this book covers: computing and simulation methods in current and future thermostability research, especially in nonempirical situations, how rigidity theory is used to improve the thermal adaptation of mesophiles Subtilisin-like serine proteases and their significant engineering applications. The state of knowledge concerning structure function relations and the origins of their structural stability. Computational and experimental approaches for the design of proteins with increased thermal stability based on sequences or three-dimensional structures. Understanding the molecular basis of how thermostable and hyperthermostable proteins gain and maintain their stability and biological function at high temperatures remains an important scientific challenge. A more detailed knowledge of protein stability not only deepens our understanding of protein structure but also helps in obtaining insights into processes that drive protein activities folding, unfolding, and misfolding essential to biological function"--Provided by publisher. |
| Beschreibung: | Includes bibliographical references. - Print version record |
| Umfang: | 1 Online-Ressource (xix, 153. [17] Seiten) illustrations |
| ISBN: | 9781439839140 143983914X 9781283274531 1283274531 9780429064128 0429064128 9781138114821 1138114820 |
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| 520 | |a "Thermostable Proteins: Structural Stability and Design provides a comprehensive, updated account of the physical basis of enhanced stability of thermophilic proteins and the design of tailor-made thermostable proteins, paving the way for their possible industrial applications. This book is devoted to understanding the survival mechanisms of "thermophilic life forms" at the molecular level with an emphasis on design strategies. The review chapters presented in Thermostable Proteins span a wide range of protein thermostability research. Basic structural, thermodynamic, and kinetic principles are explained and molecular strategies for the adaptation to high temperatures are delineated. In addition, this book covers: computing and simulation methods in current and future thermostability research, especially in nonempirical situations, how rigidity theory is used to improve the thermal adaptation of mesophiles Subtilisin-like serine proteases and their significant engineering applications. The state of knowledge concerning structure function relations and the origins of their structural stability. Computational and experimental approaches for the design of proteins with increased thermal stability based on sequences or three-dimensional structures. Understanding the molecular basis of how thermostable and hyperthermostable proteins gain and maintain their stability and biological function at high temperatures remains an important scientific challenge. A more detailed knowledge of protein stability not only deepens our understanding of protein structure but also helps in obtaining insights into processes that drive protein activities folding, unfolding, and misfolding essential to biological function"--Provided by publisher. | ||
| 650 | 0 | |a Protein engineering | |
| 650 | 0 | |a Proteins |x Analysis | |
| 650 | 0 | |a Proteins |x Conformation | |
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| 650 | 2 | |a Protein Conformation | |
| 650 | 2 | |a Thermodynamics | |
| 650 | 2 | |a Protein Engineering | |
| 650 | 4 | |a Technologie des protéines | |
| 650 | 4 | |a Protéines ; Analyse | |
| 650 | 4 | |a Protéines ; Conformation | |
| 650 | 4 | |a Thermodynamique | |
| 650 | 4 | |a thermodynamics | |
| 650 | 4 | |a Thermodynamics | |
| 650 | 4 | |a Proteins ; Conformation | |
| 650 | 4 | |a Protein engineering | |
| 650 | 4 | |a Proteins ; Analysis | |
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| id | ZDB-30-ORH-058899189 |
| illustrated | Illustrated |
| indexdate | 2025-01-17T11:20:42Z |
| institution | BVB |
| isbn | 9781439839140 143983914X 9781283274531 1283274531 9780429064128 0429064128 9781138114821 1138114820 |
| language | English |
| open_access_boolean | |
| owner | DE-91 DE-BY-TUM |
| owner_facet | DE-91 DE-BY-TUM |
| physical | 1 Online-Ressource (xix, 153. [17] Seiten) illustrations |
| psigel | ZDB-30-ORH TUM_PDA_ORH ZDB-30-ORH |
| publishDate | 2012 |
| publishDateSearch | 2012 |
| publishDateSort | 2012 |
| publisher | CRC Press |
| record_format | marc |
| spelling | Thermostable proteins structural stability and design [edited by] Srikanta Sen, Lennart Nilsson Boca Raton, Fla. CRC Press 2012 1 Online-Ressource (xix, 153. [17] Seiten) illustrations Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Includes bibliographical references. - Print version record "Thermostable Proteins: Structural Stability and Design provides a comprehensive, updated account of the physical basis of enhanced stability of thermophilic proteins and the design of tailor-made thermostable proteins, paving the way for their possible industrial applications. This book is devoted to understanding the survival mechanisms of "thermophilic life forms" at the molecular level with an emphasis on design strategies. The review chapters presented in Thermostable Proteins span a wide range of protein thermostability research. Basic structural, thermodynamic, and kinetic principles are explained and molecular strategies for the adaptation to high temperatures are delineated. In addition, this book covers: computing and simulation methods in current and future thermostability research, especially in nonempirical situations, how rigidity theory is used to improve the thermal adaptation of mesophiles Subtilisin-like serine proteases and their significant engineering applications. The state of knowledge concerning structure function relations and the origins of their structural stability. Computational and experimental approaches for the design of proteins with increased thermal stability based on sequences or three-dimensional structures. Understanding the molecular basis of how thermostable and hyperthermostable proteins gain and maintain their stability and biological function at high temperatures remains an important scientific challenge. A more detailed knowledge of protein stability not only deepens our understanding of protein structure but also helps in obtaining insights into processes that drive protein activities folding, unfolding, and misfolding essential to biological function"--Provided by publisher. Protein engineering Proteins Analysis Proteins Conformation Thermodynamics Protein Stability Protein Conformation Protein Engineering Technologie des protéines Protéines ; Analyse Protéines ; Conformation Thermodynamique thermodynamics Proteins ; Conformation Proteins ; Analysis Sen, Srikanta MitwirkendeR ctb Nilsson, Lennart 1952 November 11- MitwirkendeR ctb 9781439839133 Erscheint auch als Druck-Ausgabe 9781439839133 |
| spellingShingle | Thermostable proteins structural stability and design Protein engineering Proteins Analysis Proteins Conformation Thermodynamics Protein Stability Protein Conformation Protein Engineering Technologie des protéines Protéines ; Analyse Protéines ; Conformation Thermodynamique thermodynamics Proteins ; Conformation Proteins ; Analysis |
| title | Thermostable proteins structural stability and design |
| title_auth | Thermostable proteins structural stability and design |
| title_exact_search | Thermostable proteins structural stability and design |
| title_full | Thermostable proteins structural stability and design [edited by] Srikanta Sen, Lennart Nilsson |
| title_fullStr | Thermostable proteins structural stability and design [edited by] Srikanta Sen, Lennart Nilsson |
| title_full_unstemmed | Thermostable proteins structural stability and design [edited by] Srikanta Sen, Lennart Nilsson |
| title_short | Thermostable proteins |
| title_sort | thermostable proteins structural stability and design |
| title_sub | structural stability and design |
| topic | Protein engineering Proteins Analysis Proteins Conformation Thermodynamics Protein Stability Protein Conformation Protein Engineering Technologie des protéines Protéines ; Analyse Protéines ; Conformation Thermodynamique thermodynamics Proteins ; Conformation Proteins ; Analysis |
| topic_facet | Protein engineering Proteins Analysis Proteins Conformation Thermodynamics Protein Stability Protein Conformation Protein Engineering Technologie des protéines Protéines ; Analyse Protéines ; Conformation Thermodynamique thermodynamics Proteins ; Conformation Proteins ; Analysis |
| work_keys_str_mv | AT sensrikanta thermostableproteinsstructuralstabilityanddesign AT nilssonlennart thermostableproteinsstructuralstabilityanddesign |