Disorders of hemoglobin: genetics, pathophysiology, and clinical management
This book is a completely revised new edition of the definitive reference on disorders of hemoglobin. Authored by world-renowned experts, the book focuses on basic science aspects and clinical features of hemoglobinopathies, covering diagnosis, treatment, and future applications of current research....
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| Format: | E-Book |
| Sprache: | Englisch |
| Veröffentlicht: |
Cambridge
Cambridge University Press
2009
|
| Ausgabe: | Second edition. |
| Links: | https://doi.org/10.1017/CBO9780511596582 |
| Zusammenfassung: | This book is a completely revised new edition of the definitive reference on disorders of hemoglobin. Authored by world-renowned experts, the book focuses on basic science aspects and clinical features of hemoglobinopathies, covering diagnosis, treatment, and future applications of current research. While the second edition continues to address the important molecular, cellular, and genetic components, coverage of clinical issues has been significantly expanded, and there is more practical emphasis on diagnosis and management throughout. The book opens with a review of the scientific underpinnings. Pathophysiology of common hemoglobin disorders is discussed next in an entirely new section devoted to vascular biology, the erythrocyte membrane, nitric oxide biology, and hemolysis. Four sections deal with α and β thalassemia, sickle cell disease, and related conditions, followed by special topics. The second edition concludes with current and developing approaches to treatment, incorporating new agents for iron chelation, methods to induce fetal hemoglobin production, novel treatment approaches, stem cell transplantation, and progress in gene therapy. |
| Umfang: | 1 Online-Ressource (xx, 826 Seiten) |
| ISBN: | 9780511596582 |
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| 520 | |a This book is a completely revised new edition of the definitive reference on disorders of hemoglobin. Authored by world-renowned experts, the book focuses on basic science aspects and clinical features of hemoglobinopathies, covering diagnosis, treatment, and future applications of current research. While the second edition continues to address the important molecular, cellular, and genetic components, coverage of clinical issues has been significantly expanded, and there is more practical emphasis on diagnosis and management throughout. The book opens with a review of the scientific underpinnings. Pathophysiology of common hemoglobin disorders is discussed next in an entirely new section devoted to vascular biology, the erythrocyte membrane, nitric oxide biology, and hemolysis. Four sections deal with α and β thalassemia, sickle cell disease, and related conditions, followed by special topics. The second edition concludes with current and developing approaches to treatment, incorporating new agents for iron chelation, methods to induce fetal hemoglobin production, novel treatment approaches, stem cell transplantation, and progress in gene therapy. | ||
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| spelling | Disorders of hemoglobin genetics, pathophysiology, and clinical management edited by Martin H. Steinberg [and others] Second edition. Cambridge Cambridge University Press 2009 1 Online-Ressource (xx, 826 Seiten) txt c cr This book is a completely revised new edition of the definitive reference on disorders of hemoglobin. Authored by world-renowned experts, the book focuses on basic science aspects and clinical features of hemoglobinopathies, covering diagnosis, treatment, and future applications of current research. While the second edition continues to address the important molecular, cellular, and genetic components, coverage of clinical issues has been significantly expanded, and there is more practical emphasis on diagnosis and management throughout. The book opens with a review of the scientific underpinnings. Pathophysiology of common hemoglobin disorders is discussed next in an entirely new section devoted to vascular biology, the erythrocyte membrane, nitric oxide biology, and hemolysis. Four sections deal with α and β thalassemia, sickle cell disease, and related conditions, followed by special topics. The second edition concludes with current and developing approaches to treatment, incorporating new agents for iron chelation, methods to induce fetal hemoglobin production, novel treatment approaches, stem cell transplantation, and progress in gene therapy. Steinberg, Martin H. Erscheint auch als Druck-Ausgabe 9780521875196 |
| spellingShingle | Disorders of hemoglobin genetics, pathophysiology, and clinical management |
| title | Disorders of hemoglobin genetics, pathophysiology, and clinical management |
| title_auth | Disorders of hemoglobin genetics, pathophysiology, and clinical management |
| title_exact_search | Disorders of hemoglobin genetics, pathophysiology, and clinical management |
| title_full | Disorders of hemoglobin genetics, pathophysiology, and clinical management edited by Martin H. Steinberg [and others] |
| title_fullStr | Disorders of hemoglobin genetics, pathophysiology, and clinical management edited by Martin H. Steinberg [and others] |
| title_full_unstemmed | Disorders of hemoglobin genetics, pathophysiology, and clinical management edited by Martin H. Steinberg [and others] |
| title_short | Disorders of hemoglobin |
| title_sort | disorders of hemoglobin genetics pathophysiology and clinical management |
| title_sub | genetics, pathophysiology, and clinical management |
| work_keys_str_mv | AT steinbergmartinh disordersofhemoglobingeneticspathophysiologyandclinicalmanagement |