From loss to memory: behind the discovery of synaptic pruning

How do the billions of connections between neurons in our brain change as we learn and remember? This is the story of the discovery and the discoverer of synaptic pruning, the process of synapse elimination central to making us who we are. Taking the reader from Professor Peter Huttenlocher's c...

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Beteilige Person: Huttenlocher, Anna 1961- (VerfasserIn)
Format: Elektronisch E-Book
Sprache:Englisch
Veröffentlicht: Cambridge, United Kingdom ; New York, NY Cambridge University Press 2023
Schriftenreihe:Cambridge medicine (Series)
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Links:https://doi.org/10.1017/9781009267038
https://doi.org/10.1017/9781009267038
https://doi.org/10.1017/9781009267038
https://doi.org/10.1017/9781009267038
Zusammenfassung:How do the billions of connections between neurons in our brain change as we learn and remember? This is the story of the discovery and the discoverer of synaptic pruning, the process of synapse elimination central to making us who we are. Taking the reader from Professor Peter Huttenlocher's childhood in wartime and post-war Germany to his emigration to the US to reunite with his mother and the launch and progress of a career in medicine and research, we uncover the motivations and process of scientific discovery that led to an unexpected leap in our understanding of the human brain. Decades after the discovery, the importance of synaptic pruning to early learning, autism, schizophrenia, Alzheimer's disease and other conditions are now in the process of being uncovered
Beschreibung:Title from publisher's bibliographic system (viewed on 10 Oct 2023)
Discovering synaptic pruning -- Else, Peters mother -- Richard, Peters father, and Peters Uncle Fritz -- Greiz : Kriegskinder (Children of war) -- In Braubach, after the war -- University of Buffalo and philosophy -- Harvard Medical School -- Understanding sleep and consciousness : research at NIH -- Entering the cognitive revolution : neuroscience and cognitive psychology -- Entering the cognitive revolution : neuroscience and cognitive psychology -- Physician first, scientist second? -- Comparative brainr egions and synapse formation -- Stimulating progress on developmental brain disorders -- Neurodevelopmental disorders and schizophrenia : a role for synaptic pruning? -- Early childhood education -- Peter and Janellen's collaboration -- Microglia and the mechanisms of synaptic pruning -- Looking forward : being a physician and a scientist -- Parkinson's disease and Berlin -- Auf Deutsch -- Reflections at the end
Umfang:1 Online-Ressource (x, 149 Seiten)
ISBN:9781009267038
DOI:10.1017/9781009267038