Verfügbarkeit: Insatiable appetite | Technische Universität München

Insatiable appetite: food as cultural signifier in the Middle East and beyond

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Bibliographische Detailangaben
Weitere beteiligte Personen:	Dmitriev, Kirill 1976- (HerausgeberIn), Hauser, Julia (HerausgeberIn), Orfali, Bilal 1980- (HerausgeberIn)
Format:	Buch
Sprache:	Englisch
Veröffentlicht:	Leiden ; Boston Brill [2020]
Schlagwörter:	Nahrung Nordafrika Naher Osten Aufsatzsammlung
Links:	https://swbplus.bsz-bw.de/bsz1677421509inh.htm http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=033879881&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
Umfang:	XI, 362 Seiten Illustrationen 24 cm
ISBN:	9789004407626 9789004413023

Internformat

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Datensatz im Suchindex

_version_	1819333723780284416
adam_text	INHALTSVERZEICHNIS ABKUERZUNGSVERZEICHNIS 2 1 EINLEITUNG 3 1.1 G LIOBLASTOM E............................................................................................... 3 1.1.1 AETIOLOGIE & EPIDEMIOLOGIE............................................................... 3 1.1.2 DIAGNOSTIK . . ................................................................................... 5 1.1.3 THERAPIE ................................................................................... ... . 8 1.1.4 LANGZEITUEBERLEBEN........................................................................... 12 1.2 DNA-METHYLIERUNG IM MENSCHLICHEN G E N O M ............................................. 13 1.3 DNA-METHYLIERUNG IN DER TUMORGENESE...................................................... 15 1.4 Z IELSETZUNG...................................................................................... 17 2 MATERIAL UND METHODEN 19 2.1 STUDIENKOLLEKTIVE......................................................................................... 19 2.1.1 LTS/STS KOLLEKTIV........................................................................... 19 2.1.2 NORMALHIMPROBEN.......................................................................... 19 2.1.3 VALIDIERUNGSKOLLEKTIVE..................................................................... 20 2.1.4 ETHIKVOTUM...................................................................................... 21 2.2 M ATERIAL.................................................................................................. 22 2.3 M ETHODEN..................................................................................................... 26 2.3.1 BEURTEILUNG VON GEWEBEPROBEN...................................................... 26 2.3.2 DNA-EXTRAKTION............................................................................. 26 2.3.3 DNA-FRAGMENTIERUNG.................................................................... 26 2.3.4 METHYL-CPG IMMUNPRAEZIPITATION (M C IP )....................................... 27 2.3.5 MICROARRAYANALYSE.......................................................................... 29 2.3.6 MASSARRAY . ................................................................................... 30 2.4 STATISTISCHE UND BIOINFORMATISCHE A N ALY SEN ................................................ 34 2.4.1 PRAEPROZESSIERUNG UND NORMALISIERUNG DER MICROARRAYDATEN............. 34 2.4.2 HYPOTHESENTESTS .............................................................................. 34 2.4.3 UEBERLEBENSANALYSE........................................................................... 35 2.4.4 REPRODUZIERBARE DATENANALYSE......................................................... 35 3 ERGEBNISSE 39 3.1 ANREICHERUNG METHYLIERTER DNA-FRAGMENTE................................................ 39 3.2 AUSSCHLUSS EINES G -C IM P ........................................................................... 41 3.3 GENOMWEITE DNA-METHYLIERUNGSANALYSE................................................... 42 3.4 DIFFERENZIELL METHYLIERTE REGIONEN IN LTS UND S T S .................................... 44 3.5 UNTERSUCHUNG DER DMR MITTELS MASSARRAY............................................. 45 3.6 METHYLIERUNG DER LOC283731/ISLR2 PROMOTOREN....................................... 47 3.7 MUTATIONEN IM LOC283731/ISLR2 LOKUS . . . ............................................ 48 3.8 PROGNOSEFAEHIGKEIT IM TCGA VALIDIERUNGSKOLLEKTIV.................................... 49 3.9 PROGNOSEFAEHIGKEIT IM HEIDELBERG VALIDIERUNGSKOLLEKTIV .............................. 52 3.10 LOC283731 UND MGMT SIND NICHT KOM ETHYLIERT ....................................... 53 4 DISKUSSION 55 4.1 ANSATZ DER BIOMARKERENTWICKLUNG............................................................... 55 4.2 MCIP UND MICROARRAYANALYSE ....................................................................... 56 4.3 VALIDERUNG MITTELS MASSARRAY.................................................................. 59 4.4 PUBLIZIERTE BIOMARKERSTUDIEN........................................................................ 59 4.5 REPRODUZIERBARE DATENANALYSE..................................................................... 61 4.6 LOC283731 PROMOTORMETHYLIERUNG............................................................ 62 4.7 INTEGRATIVE HIMTUMORDIAGNOSTIK ................................................................. 63 4.8 AUSBLICK........................................................................................................ 64 5 ZUSAMMENFASSUNG 65 LITERATURVERZEICHNIS 67 EIGENE VEROEFFENTLICHUNGEN 79 LEBENSLAUF 83 DANKSAGUNG 85 EIDESSTATTLICHE VERSICHERUNG 87
any_adam_object	1
author2	Dmitriev, Kirill 1976- Hauser, Julia Orfali, Bilal 1980-
author2_role	edt edt edt
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dewey-full	939.4-956
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dewey-ones	939 - Other parts of ancient world
dewey-raw	939.4-956
dewey-search	939.4-956
dewey-sort	3939.4 3956
dewey-tens	930 - History of ancient world to ca. 499
discipline	Geschichte Sozial-/Kulturanthropologie / Empirische Kulturwissenschaft
format	Book
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geographic_facet	Nordafrika Naher Osten
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isbn	9789004407626 9789004413023
language	English
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open_access_boolean
owner	DE-19 DE-BY-UBM DE-188
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physical	XI, 362 Seiten Illustrationen 24 cm
publishDate	2020
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publishDateSort	2020
publisher	Brill
record_format	marc
spellingShingle	Insatiable appetite food as cultural signifier in the Middle East and beyond Nahrung (DE-588)4171117-8 gnd
subject_GND	(DE-588)4171117-8 (DE-588)4042482-0 (DE-588)4068878-1 (DE-588)4143413-4
title	Insatiable appetite food as cultural signifier in the Middle East and beyond
title_auth	Insatiable appetite food as cultural signifier in the Middle East and beyond
title_exact_search	Insatiable appetite food as cultural signifier in the Middle East and beyond
title_full	Insatiable appetite food as cultural signifier in the Middle East and beyond edited by Kirill Dmitriev, Julia Hauser, Bilal Orfali
title_fullStr	Insatiable appetite food as cultural signifier in the Middle East and beyond edited by Kirill Dmitriev, Julia Hauser, Bilal Orfali
title_full_unstemmed	Insatiable appetite food as cultural signifier in the Middle East and beyond edited by Kirill Dmitriev, Julia Hauser, Bilal Orfali
title_short	Insatiable appetite
title_sort	insatiable appetite food as cultural signifier in the middle east and beyond
title_sub	food as cultural signifier in the Middle East and beyond
topic	Nahrung (DE-588)4171117-8 gnd
topic_facet	Nahrung Nordafrika Naher Osten Aufsatzsammlung
url	https://swbplus.bsz-bw.de/bsz1677421509inh.htm http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=033879881&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
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Verfügbarkeit

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Inhaltsverzeichnis