Evaluating growth and differentiation of testicular tissue by ex vivo approaches:
Gespeichert in:
| Beteilige Person: | |
|---|---|
| Format: | Hochschulschrift/Dissertation Buch |
| Sprache: | Englisch |
| Veröffentlicht: |
Münster
2018
|
| Schlagwörter: | |
| Links: | http://d-nb.info/1157027628/04 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=030805071&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| Umfang: | VIII Blätter, 144 Seiten Illustrationen 30 cm |
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| 245 | 1 | 0 | |a Evaluating growth and differentiation of testicular tissue by ex vivo approaches |c vorgelegt von: Swati Sharma |
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Datensatz im Suchindex
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|---|---|
| adam_text | TABLE OF CONTENTS
1. INTRODUCTION
1.1 CHARACTERISTICS OF GERMLINE STEM CELLS
1.2 MALE GERMLINE DEVELOPMENT
1.3 TESTICULAR ORGANIZATION
1.3.1 PRIMATES VERSUS OTHER SPECIES
1.3.2 PRIMATE PHYLOGENY
1.3.3 TESTICULAR DEVELOPMENT IN NON-HUMAN PRIMATES
1.3.4 STRUCTURAL AND FUNCTIONAL ORGANIZATION OF A TESTIS
1.4 CLONAL KINETICS: PRIMATES VERSUS OTHER SPECIES
1.5 GERM CELL EXPRESSION IN PRIMATES
1.6 ROLE OF TESTICULAR NICHE AND MICROENVIRONMENT IN STEM CELL
FATE DECISIONS
1.7 CURRENT STATE OF PROGRESS IN ESTABLISHING EX VIVO MODELS FOR
STUDYING SPERMATOGENESIS
1.7.1 XENOGRAFTING
1.7.2 ORGAN CULTURE
1.7.3 SSC CULTURE
1.8 RATIONALE AND HYPOTHESIS
2. AIM
2.1 GENERAL AIM
2.2 SPECIFIC AIMS
3. MATERIALS AND METHODS
3.1 EXPERIMENTAL SCHEME
3.2 ETHICAL REGULATIONS FOR ANIMAL USE
3.3 EXPERIMENT 1: NEONATAL MARMOSET ORGAN CULTURE
3.4 EXPERIMENT 2: PREPUBERTAL MARMOSET XENOGRAFTING
3.5 EXPERIMENT 3: PREPUBERTAL MARMOSET SSC CULTURE
PAGE NUMBERS
1-24
25-27
28-45
3.6 EXPERIMENT 4: ADULT MACAQUE SSC CULTURE
3.7 REVIEW
4. RESULTS 46-74
4.1 EXPERIMENT 1: NEONATAL MARMOSET ORGAN CULTURE
4.2 EXPERIMENT 2: PREPUBERTAL MARMOSET XENOGRAFTING
4.3 EXPERIMENT 3: PREPUBERTAL MARMOSET SSC CULTURE
4.4 EXPERIMENT 4: ADULT MACAQUE SSC CULTURE
4.5 REVIEW
5. DISCUSSION 75-97
5.1 EFFECT OF NICHE FACTORS ON IN VITRO CULTURES
5.1.1 EVALUATING GERM CELL EXPRESSION IN IN VITRO MARMOSET SSC CULTURES
5.1.2 A. EVALUATING GERM CELL EXPRESSION IN IN VITRO MACAQUE SSC
CULTURES
B. EVALUATING CLONAL DYNAMICS IN IN VITRO MACAQUE SSC CULTURES
5.2 EFFECT OF SERUM ON CULTURED NEONATAL MARMOSET TESTICULAR FRAGMENTS
5.3 EFFECT OF NICHE AND ENDOCRINE FACTORS ON SPERMATOGENIC INDUCTION IN
MARMOSET
TESTICULAR XENOGRAFTS
5.4 GERM CELL HETEROGENEITY
5.5 EVOLUTIONARY VIEW (PROPOSED MODEL)
5.6 OVERALL CONCLUSIONS
6. SUMMARY 98-99
6.1 EXPERIMENT!: NEONATAL MARMOSET ORGAN CULTURE
6.2 EXPERIMENT 2: PREPUBERTAL MARMOSET XENOGRAFTING
6.3 EXPERIMENT 3: PREPUBERTAL MARMOSET SSC CULTURE
6.4 EXPERIMENT 4: ADULT MACAQUE SSC CULTURE
7. OUTLOOK 100-106
8. REFERENCES
107-127
9. ACKNOWLEDGEMENT
128-129
10. SUPPLEMENTARY DATA
130-132
11. ABBREVIATIONS
133-136
12. CV
137-144
|
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| ctrlnum | (OCoLC)1034653566 (DE-599)DNB1157027628 |
| discipline | Biologie |
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| spellingShingle | Sharma, Swati Evaluating growth and differentiation of testicular tissue by ex vivo approaches |
| subject_GND | (DE-588)4113937-9 |
| title | Evaluating growth and differentiation of testicular tissue by ex vivo approaches |
| title_auth | Evaluating growth and differentiation of testicular tissue by ex vivo approaches |
| title_exact_search | Evaluating growth and differentiation of testicular tissue by ex vivo approaches |
| title_full | Evaluating growth and differentiation of testicular tissue by ex vivo approaches vorgelegt von: Swati Sharma |
| title_fullStr | Evaluating growth and differentiation of testicular tissue by ex vivo approaches vorgelegt von: Swati Sharma |
| title_full_unstemmed | Evaluating growth and differentiation of testicular tissue by ex vivo approaches vorgelegt von: Swati Sharma |
| title_short | Evaluating growth and differentiation of testicular tissue by ex vivo approaches |
| title_sort | evaluating growth and differentiation of testicular tissue by ex vivo approaches |
| topic_facet | Hochschulschrift |
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