Protective signaling networks in neuroinflammation - the transcription factor Nrf2 and the Ang-(1-7)/Mas axis: = Protektive Signalwege in der Neuroinflammation - der Transkriptionsfaktor Nrf2 und die Ang-(1-7)/Mas Achse
Gespeichert in:
| Beteilige Person: | |
|---|---|
| Format: | Hochschulschrift/Dissertation Buch |
| Sprache: | Englisch |
| Veröffentlicht: |
Erlangen ; Nürnberg
[2018]
|
| Schlagwörter: | |
| Links: | http://d-nb.info/1164199498/04 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=030592567&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| Beschreibung: | Enthält Sonderabdrucke |
| Umfang: | 54 Seiten, 42 verschieden gezählte Seiten Illustrationen, Diagramme 30 cm |
Internformat
MARC
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| 245 | 1 | 0 | |a Protective signaling networks in neuroinflammation - the transcription factor Nrf2 and the Ang-(1-7)/Mas axis |b = Protektive Signalwege in der Neuroinflammation - der Transkriptionsfaktor Nrf2 und die Ang-(1-7)/Mas Achse |c vorgelegt von Anna Hammer |
| 246 | 1 | 3 | |a Protektive Signalwege in der Neuroinflammation - der Transkriptionsfaktor Nrf2 und die Ang-(1-7)/Mas Achse |
| 246 | 1 | 1 | |a Protektive Signalwege in der Neuroinflammation - der Transkriptionsfaktor Nrf2 und die Ang-(1-7)/Mas Achse |
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Datensatz im Suchindex
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|---|---|
| adam_text | TABLE OF CONTENTS
I.
ABSTRACT................................................................................................................................................................
1
II.
ZUSAMMENFASSUNG..............................................................................................................................................
3
1.
INTRODUCTION........................................................................................................................................................
5
1.1 MULTIPLE SCLEROSIS - ETIOLOGY, EPIDEMIOLOGY AND CLINICAL
ASPECTS..........................................................5
1.2 MULTIPLE SCLEROSIS -
PATHOGENESIS...............................................................................................................7
1.3 TRANSLATION OF ASPECTS OF MS PATHOGENESIS TO THE ANIMAL
MODEL........................................................9
2. PUBLICATIONS -
RESULTS.....................................................................................................................................11
2.1 ROLE OF OXIDATIVE STRESS IN
NEUROINFLAMMATION.....................................................................................
11
2.1.1 THE NRF2 PATHWAY IN DENDRITIC CELL BIOLOGY (HAMMER ET AL. 2 01 7)
.............................................
14
2.1.2 LINKING NRF2 SIGNALING AND DMF TREATMENT EFFICACY IN MS PATIENTS
(HAMMER ET AL. 2018) 16
2.2 THE RENIN-ANGIOTENSIN SYSTEM IN
AUTOIMMUNITY...................................................................................19
2.2.1 ROLE OF THE ANG-(L-7)/M AS AXIS AS AN ALTERNATIVE
RENIN-ANGIOTENSIN SYSTEM IN MACROPHAGE-
MEDIATED INFLAMMATION (HAMMER ET AL. 2 0 1 6
)...................................................................22
3. DISCUSSION - PROTECTIVE SIGNALING NETWORKS IN NEUROINFLAMMATION
.........................................................
25
3.1 THE NRF2 SIGNALING PATHWAY - KEY MEDIATOR IN OXIDATIVE STRESS AND
VITAL THERAPEUTIC TARGET IN
MULTIPLE
SCLEROSIS........................................................................................................................................
25
3.2 ANG-(L-7)/M AS - THE PROTECTIVE ARM OF THE RENIN-ANGIOTENSIN SYSTEM
............................................
27
3.3 INTEGRATING SIGNALING NETWORKS TO BETTER UNDERSTAND MULTIPLE
SCLEROSIS PATHOGENESIS
................
29
4.
REFERENCES...........................................................................................................
31
5.
APPENDIX...........................................................................................................................................................
47
5.1 AUTHOR
CONTRIBUTIONS.................................................................................................................................
47
5.2 LIST OF
ABBREVIATIONS..................................................................................................................................
49
5.3 LIST OF
PUBLICATIONS.....................................................................................................................................51
5.4 CONFERENCE
CONTRIBUTIONS........................................................................................................................
52
5.5 CURRICULUM
VITAE.........................................................................................................................................
53
|
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| id | DE-604.BV045203652 |
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| indexdate | 2024-12-20T18:20:42Z |
| institution | BVB |
| language | English |
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| spellingShingle | Hammer, Anna 1988- Protective signaling networks in neuroinflammation - the transcription factor Nrf2 and the Ang-(1-7)/Mas axis = Protektive Signalwege in der Neuroinflammation - der Transkriptionsfaktor Nrf2 und die Ang-(1-7)/Mas Achse |
| subject_GND | (DE-588)4113937-9 |
| title | Protective signaling networks in neuroinflammation - the transcription factor Nrf2 and the Ang-(1-7)/Mas axis = Protektive Signalwege in der Neuroinflammation - der Transkriptionsfaktor Nrf2 und die Ang-(1-7)/Mas Achse |
| title_alt | Protektive Signalwege in der Neuroinflammation - der Transkriptionsfaktor Nrf2 und die Ang-(1-7)/Mas Achse |
| title_auth | Protective signaling networks in neuroinflammation - the transcription factor Nrf2 and the Ang-(1-7)/Mas axis = Protektive Signalwege in der Neuroinflammation - der Transkriptionsfaktor Nrf2 und die Ang-(1-7)/Mas Achse |
| title_exact_search | Protective signaling networks in neuroinflammation - the transcription factor Nrf2 and the Ang-(1-7)/Mas axis = Protektive Signalwege in der Neuroinflammation - der Transkriptionsfaktor Nrf2 und die Ang-(1-7)/Mas Achse |
| title_full | Protective signaling networks in neuroinflammation - the transcription factor Nrf2 and the Ang-(1-7)/Mas axis = Protektive Signalwege in der Neuroinflammation - der Transkriptionsfaktor Nrf2 und die Ang-(1-7)/Mas Achse vorgelegt von Anna Hammer |
| title_fullStr | Protective signaling networks in neuroinflammation - the transcription factor Nrf2 and the Ang-(1-7)/Mas axis = Protektive Signalwege in der Neuroinflammation - der Transkriptionsfaktor Nrf2 und die Ang-(1-7)/Mas Achse vorgelegt von Anna Hammer |
| title_full_unstemmed | Protective signaling networks in neuroinflammation - the transcription factor Nrf2 and the Ang-(1-7)/Mas axis = Protektive Signalwege in der Neuroinflammation - der Transkriptionsfaktor Nrf2 und die Ang-(1-7)/Mas Achse vorgelegt von Anna Hammer |
| title_short | Protective signaling networks in neuroinflammation - the transcription factor Nrf2 and the Ang-(1-7)/Mas axis |
| title_sort | protective signaling networks in neuroinflammation the transcription factor nrf2 and the ang 1 7 mas axis protektive signalwege in der neuroinflammation der transkriptionsfaktor nrf2 und die ang 1 7 mas achse |
| title_sub | = Protektive Signalwege in der Neuroinflammation - der Transkriptionsfaktor Nrf2 und die Ang-(1-7)/Mas Achse |
| topic_facet | Hochschulschrift |
| url | http://d-nb.info/1164199498/04 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=030592567&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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