Protein Folding, Misfolding, and Disease: Methods and Protocols
Protein misfolding is a key feature of many disorders in humans, given that over twenty proteins are known to misfold and cause disease. In Protein Folding, Misfolding, and Disease: Methods and Protocols, experts in the field present a collection of current methods for studying the analysis of prot...
Gespeichert in:
| Weitere beteiligte Personen: | , , , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | Englisch |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2011
|
| Schriftenreihe: | Methods in Molecular Biology, Methods and Protocols
752 |
| Schlagwörter: | |
| Links: | https://doi.org/10.1007/978-1-60327-223-0 https://doi.org/10.1007/978-1-60327-223-0 https://doi.org/10.1007/978-1-60327-223-0 |
| Zusammenfassung: | Protein misfolding is a key feature of many disorders in humans, given that over twenty proteins are known to misfold and cause disease. In Protein Folding, Misfolding, and Disease: Methods and Protocols, experts in the field present a collection of current methods for studying the analysis of protein folding and misfolding, featuring strategies for expressing and refolding recombinant proteins which can then be utilized in subsequent experiments. This detailed volume also covers methods for analyzing the formation of amyloid, protocols for determining the size and structure of native and misfolded proteins, as well as specific examples of where misfolded proteins can be examined using state-of –the-art technologies. Written in the highly successful Methods in Molecular Biology™ series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Up to date and authoritative, Protein Folding, Misfolding, and Disease: Methods and Protocols offers researchers the tools necessary to move ahead in this vital field |
| Umfang: | 1 Online-Ressource (X, 230 p. 50 illus) |
| ISBN: | 9781603272230 |
| DOI: | 10.1007/978-1-60327-223-0 |
Internformat
MARC
| LEADER | 00000nam a2200000zcb4500 | ||
|---|---|---|---|
| 001 | BV044951967 | ||
| 003 | DE-604 | ||
| 005 | 20181012 | ||
| 007 | cr|uuu---uuuuu | ||
| 008 | 180517s2011 xx o|||| 00||| eng d | ||
| 020 | |a 9781603272230 |9 978-1-60327-223-0 | ||
| 024 | 7 | |a 10.1007/978-1-60327-223-0 |2 doi | |
| 035 | |a (ZDB-2-PRO)978-1-60327-223-0 | ||
| 035 | |a (OCoLC)1036302121 | ||
| 035 | |a (DE-599)BVBBV044951967 | ||
| 040 | |a DE-604 |b ger |e rda | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-355 |a DE-91 | ||
| 082 | 0 | |a 572.6 |2 23 | |
| 084 | |a WC 4170 |0 (DE-625)148093: |2 rvk | ||
| 084 | |a WD 5100 |0 (DE-625)148194: |2 rvk | ||
| 245 | 1 | 0 | |a Protein Folding, Misfolding, and Disease |b Methods and Protocols |c edited by Andrew F. Hill, Kevin J. Barnham, Stephen P. Bottomley, Roberto Cappai |
| 264 | 1 | |a Totowa, NJ |b Humana Press |c 2011 | |
| 300 | |a 1 Online-Ressource (X, 230 p. 50 illus) | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b c |2 rdamedia | ||
| 338 | |b cr |2 rdacarrier | ||
| 490 | 0 | |a Methods in Molecular Biology, Methods and Protocols |v 752 | |
| 520 | |a Protein misfolding is a key feature of many disorders in humans, given that over twenty proteins are known to misfold and cause disease. In Protein Folding, Misfolding, and Disease: Methods and Protocols, experts in the field present a collection of current methods for studying the analysis of protein folding and misfolding, featuring strategies for expressing and refolding recombinant proteins which can then be utilized in subsequent experiments. This detailed volume also covers methods for analyzing the formation of amyloid, protocols for determining the size and structure of native and misfolded proteins, as well as specific examples of where misfolded proteins can be examined using state-of –the-art technologies. Written in the highly successful Methods in Molecular Biology™ series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Up to date and authoritative, Protein Folding, Misfolding, and Disease: Methods and Protocols offers researchers the tools necessary to move ahead in this vital field | ||
| 650 | 4 | |a Life Sciences | |
| 650 | 4 | |a Protein Science | |
| 650 | 4 | |a Pathology | |
| 650 | 4 | |a Life sciences | |
| 650 | 4 | |a Pathology | |
| 650 | 4 | |a Proteins | |
| 650 | 0 | 7 | |a Konformationsänderung |0 (DE-588)4164966-7 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Proteinfaltung |0 (DE-588)4324567-5 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Labortechnik |0 (DE-588)4123602-6 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Pathophysiologie |0 (DE-588)4044898-8 |2 gnd |9 rswk-swf |
| 689 | 0 | 0 | |a Proteinfaltung |0 (DE-588)4324567-5 |D s |
| 689 | 0 | 1 | |a Konformationsänderung |0 (DE-588)4164966-7 |D s |
| 689 | 0 | 2 | |a Pathophysiologie |0 (DE-588)4044898-8 |D s |
| 689 | 0 | |5 DE-604 | |
| 689 | 1 | 0 | |a Proteinfaltung |0 (DE-588)4324567-5 |D s |
| 689 | 1 | 1 | |a Konformationsänderung |0 (DE-588)4164966-7 |D s |
| 689 | 1 | 2 | |a Labortechnik |0 (DE-588)4123602-6 |D s |
| 689 | 1 | |C b |5 DE-604 | |
| 700 | 1 | |a Hill, Andrew F. |4 edt | |
| 700 | 1 | |a Barnham, Kevin J. |4 edt | |
| 700 | 1 | |a Bottomley, Stephen P. |4 edt | |
| 700 | 1 | |a Cappai, Roberto |4 edt | |
| 776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 9781603272216 |
| 856 | 4 | 0 | |u https://doi.org/10.1007/978-1-60327-223-0 |x Verlag |z URL des Erstveröffentlichers |3 Volltext |
| 912 | |a ZDB-2-PRO | ||
| 943 | 1 | |a oai:aleph.bib-bvb.de:BVB01-030344723 | |
| 966 | e | |u https://doi.org/10.1007/978-1-60327-223-0 |l DE-355 |p ZDB-2-PRO |x Verlag |3 Volltext | |
| 966 | e | |u https://doi.org/10.1007/978-1-60327-223-0 |l DE-91 |p ZDB-2-PRO |x Verlag |3 Volltext | |
Datensatz im Suchindex
| DE-BY-TUM_katkey | 2644209 |
|---|---|
| _version_ | 1821936315284848641 |
| any_adam_object | |
| author2 | Hill, Andrew F. Barnham, Kevin J. Bottomley, Stephen P. Cappai, Roberto |
| author2_role | edt edt edt edt |
| author2_variant | a f h af afh k j b kj kjb s p b sp spb r c rc |
| author_facet | Hill, Andrew F. Barnham, Kevin J. Bottomley, Stephen P. Cappai, Roberto |
| building | Verbundindex |
| bvnumber | BV044951967 |
| classification_rvk | WC 4170 WD 5100 |
| collection | ZDB-2-PRO |
| ctrlnum | (ZDB-2-PRO)978-1-60327-223-0 (OCoLC)1036302121 (DE-599)BVBBV044951967 |
| dewey-full | 572.6 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 572 - Biochemistry |
| dewey-raw | 572.6 |
| dewey-search | 572.6 |
| dewey-sort | 3572.6 |
| dewey-tens | 570 - Biology |
| discipline | Biologie |
| doi_str_mv | 10.1007/978-1-60327-223-0 |
| format | Electronic eBook |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>03659nam a2200649zcb4500</leader><controlfield tag="001">BV044951967</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">20181012 </controlfield><controlfield tag="007">cr|uuu---uuuuu</controlfield><controlfield tag="008">180517s2011 xx o|||| 00||| eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9781603272230</subfield><subfield code="9">978-1-60327-223-0</subfield></datafield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/978-1-60327-223-0</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ZDB-2-PRO)978-1-60327-223-0</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)1036302121</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV044951967</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rda</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-355</subfield><subfield code="a">DE-91</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">572.6</subfield><subfield code="2">23</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">WC 4170</subfield><subfield code="0">(DE-625)148093:</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">WD 5100</subfield><subfield code="0">(DE-625)148194:</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Protein Folding, Misfolding, and Disease</subfield><subfield code="b">Methods and Protocols</subfield><subfield code="c">edited by Andrew F. Hill, Kevin J. Barnham, Stephen P. Bottomley, Roberto Cappai</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Totowa, NJ</subfield><subfield code="b">Humana Press</subfield><subfield code="c">2011</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 Online-Ressource (X, 230 p. 50 illus)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="0" ind2=" "><subfield code="a">Methods in Molecular Biology, Methods and Protocols</subfield><subfield code="v">752</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Protein misfolding is a key feature of many disorders in humans, given that over twenty proteins are known to misfold and cause disease. In Protein Folding, Misfolding, and Disease: Methods and Protocols, experts in the field present a collection of current methods for studying the analysis of protein folding and misfolding, featuring strategies for expressing and refolding recombinant proteins which can then be utilized in subsequent experiments. This detailed volume also covers methods for analyzing the formation of amyloid, protocols for determining the size and structure of native and misfolded proteins, as well as specific examples of where misfolded proteins can be examined using state-of –the-art technologies. Written in the highly successful Methods in Molecular Biology™ series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Up to date and authoritative, Protein Folding, Misfolding, and Disease: Methods and Protocols offers researchers the tools necessary to move ahead in this vital field</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Life Sciences</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Protein Science</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Pathology</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Life sciences</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Pathology</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Proteins</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Konformationsänderung</subfield><subfield code="0">(DE-588)4164966-7</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Proteinfaltung</subfield><subfield code="0">(DE-588)4324567-5</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Labortechnik</subfield><subfield code="0">(DE-588)4123602-6</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Pathophysiologie</subfield><subfield code="0">(DE-588)4044898-8</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Proteinfaltung</subfield><subfield code="0">(DE-588)4324567-5</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">Konformationsänderung</subfield><subfield code="0">(DE-588)4164966-7</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="2"><subfield code="a">Pathophysiologie</subfield><subfield code="0">(DE-588)4044898-8</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="689" ind1="1" ind2="0"><subfield code="a">Proteinfaltung</subfield><subfield code="0">(DE-588)4324567-5</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2="1"><subfield code="a">Konformationsänderung</subfield><subfield code="0">(DE-588)4164966-7</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2="2"><subfield code="a">Labortechnik</subfield><subfield code="0">(DE-588)4123602-6</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2=" "><subfield code="C">b</subfield><subfield code="5">DE-604</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Hill, Andrew F.</subfield><subfield code="4">edt</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Barnham, Kevin J.</subfield><subfield code="4">edt</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Bottomley, Stephen P.</subfield><subfield code="4">edt</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Cappai, Roberto</subfield><subfield code="4">edt</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe</subfield><subfield code="z">9781603272216</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1007/978-1-60327-223-0</subfield><subfield code="x">Verlag</subfield><subfield code="z">URL des Erstveröffentlichers</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-2-PRO</subfield></datafield><datafield tag="943" ind1="1" ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-030344723</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://doi.org/10.1007/978-1-60327-223-0</subfield><subfield code="l">DE-355</subfield><subfield code="p">ZDB-2-PRO</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://doi.org/10.1007/978-1-60327-223-0</subfield><subfield code="l">DE-91</subfield><subfield code="p">ZDB-2-PRO</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield></record></collection> |
| id | DE-604.BV044951967 |
| illustrated | Not Illustrated |
| indexdate | 2024-12-20T18:15:06Z |
| institution | BVB |
| isbn | 9781603272230 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-030344723 |
| oclc_num | 1036302121 |
| open_access_boolean | |
| owner | DE-355 DE-BY-UBR DE-91 DE-BY-TUM |
| owner_facet | DE-355 DE-BY-UBR DE-91 DE-BY-TUM |
| physical | 1 Online-Ressource (X, 230 p. 50 illus) |
| psigel | ZDB-2-PRO |
| publishDate | 2011 |
| publishDateSearch | 2011 |
| publishDateSort | 2011 |
| publisher | Humana Press |
| record_format | marc |
| series2 | Methods in Molecular Biology, Methods and Protocols |
| spellingShingle | Protein Folding, Misfolding, and Disease Methods and Protocols Life Sciences Protein Science Pathology Life sciences Proteins Konformationsänderung (DE-588)4164966-7 gnd Proteinfaltung (DE-588)4324567-5 gnd Labortechnik (DE-588)4123602-6 gnd Pathophysiologie (DE-588)4044898-8 gnd |
| subject_GND | (DE-588)4164966-7 (DE-588)4324567-5 (DE-588)4123602-6 (DE-588)4044898-8 |
| title | Protein Folding, Misfolding, and Disease Methods and Protocols |
| title_auth | Protein Folding, Misfolding, and Disease Methods and Protocols |
| title_exact_search | Protein Folding, Misfolding, and Disease Methods and Protocols |
| title_full | Protein Folding, Misfolding, and Disease Methods and Protocols edited by Andrew F. Hill, Kevin J. Barnham, Stephen P. Bottomley, Roberto Cappai |
| title_fullStr | Protein Folding, Misfolding, and Disease Methods and Protocols edited by Andrew F. Hill, Kevin J. Barnham, Stephen P. Bottomley, Roberto Cappai |
| title_full_unstemmed | Protein Folding, Misfolding, and Disease Methods and Protocols edited by Andrew F. Hill, Kevin J. Barnham, Stephen P. Bottomley, Roberto Cappai |
| title_short | Protein Folding, Misfolding, and Disease |
| title_sort | protein folding misfolding and disease methods and protocols |
| title_sub | Methods and Protocols |
| topic | Life Sciences Protein Science Pathology Life sciences Proteins Konformationsänderung (DE-588)4164966-7 gnd Proteinfaltung (DE-588)4324567-5 gnd Labortechnik (DE-588)4123602-6 gnd Pathophysiologie (DE-588)4044898-8 gnd |
| topic_facet | Life Sciences Protein Science Pathology Life sciences Proteins Konformationsänderung Proteinfaltung Labortechnik Pathophysiologie |
| url | https://doi.org/10.1007/978-1-60327-223-0 |
| work_keys_str_mv | AT hillandrewf proteinfoldingmisfoldinganddiseasemethodsandprotocols AT barnhamkevinj proteinfoldingmisfoldinganddiseasemethodsandprotocols AT bottomleystephenp proteinfoldingmisfoldinganddiseasemethodsandprotocols AT cappairoberto proteinfoldingmisfoldinganddiseasemethodsandprotocols |