The renin-angiotensin system and progression of renal diseases:
The renin-angiotensin system (RAS) has long been seen as a systemic endocrine system in which angiotensin II (ANG II) is solely involved in blood pressure regulation and the mediation of aldosterone release. However, it is now known that specific organ systems exhibit their own local RAS, functionin...
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| Format: | Elektronisch E-Book |
| Sprache: | Englisch |
| Veröffentlicht: |
Basel
Karger
2001
|
| Schriftenreihe: | Contributions to nephrology
Vol. 135 |
| Schlagwörter: | |
| Links: | https://karger.com/books/book/2393 https://karger.com/books/book/2393 https://karger.com/books/book/2393 https://karger.com/books/book/2393 https://karger.com/books/book/2393 https://karger.com/books/book/2393 https://karger.com/books/book/2393 https://karger.com/books/book/2393 https://karger.com/books/book/2393 https://karger.com/books/book/2393 https://karger.com/books/book/2393 https://karger.com/books/book/2393 https://karger.com/books/book/2393 https://karger.com/books/book/2393 https://karger.com/books/book/2393 https://karger.com/books/book/2393 https://karger.com/books/book/2393 https://karger.com/books/book/2393 https://karger.com/books/book/2393 https://karger.com/books/book/2393 https://karger.com/books/book/2393 https://karger.com/books/book/2393 https://karger.com/books/book/2393 https://karger.com/books/book/2393 https://karger.com/books/book/2393 https://karger.com/books/book/2393 https://karger.com/books/book/2393 https://karger.com/books/book/2393 https://karger.com/books/book/2393 https://karger.com/books/book/2393 https://karger.com/books/book/2393 https://karger.com/books/book/2393 |
| Zusammenfassung: | The renin-angiotensin system (RAS) has long been seen as a systemic endocrine system in which angiotensin II (ANG II) is solely involved in blood pressure regulation and the mediation of aldosterone release. However, it is now known that specific organ systems exhibit their own local RAS, functioning for the most part independently from their systemic counterpart. A deluge of data from the last decade has shown that ANG II displays many more functions than just regulating blood pressure: ANG II is a growth factor, exhibits profibrogenic actions, and even serves as a proinflammatory cytokine. It is now clear that this peptide plays a pivotal role in the progression of chronic kidney disease towards endstage renal failure. Clinical studies have provided compelling evidence that interference with ANG II slows this deterioration of renal function.This publication presents the first comprehensive summary of this important topic: Basic concepts as well as clinical aspects of the RAS are reviewed by international experts who made many of the key discoveries that constitute our contemporary understanding of ANG II as a central factor in the progression of renal disease. This publication should be read by physicians treating patients with chronic renal diseases (internists, nephrologists and urologists). Moreover, basic scientists such as renal physiologists, renal pathologists and biochemists who want a comprehensive overview of the subject will profit from reading this book |
| Beschreibung: | from basic concepts to clinical aspects |
| Umfang: | 1 Online-Ressource (X, 268 Seiten) Illustrationen, Diagramme |
| ISBN: | 9783318007480 |
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| 520 | |a The renin-angiotensin system (RAS) has long been seen as a systemic endocrine system in which angiotensin II (ANG II) is solely involved in blood pressure regulation and the mediation of aldosterone release. However, it is now known that specific organ systems exhibit their own local RAS, functioning for the most part independently from their systemic counterpart. A deluge of data from the last decade has shown that ANG II displays many more functions than just regulating blood pressure: ANG II is a growth factor, exhibits profibrogenic actions, and even serves as a proinflammatory cytokine. It is now clear that this peptide plays a pivotal role in the progression of chronic kidney disease towards endstage renal failure. Clinical studies have provided compelling evidence that interference with ANG II slows this deterioration of renal function.This publication presents the first comprehensive summary of this important topic: Basic concepts as well as clinical aspects of the RAS are reviewed by international experts who made many of the key discoveries that constitute our contemporary understanding of ANG II as a central factor in the progression of renal disease. This publication should be read by physicians treating patients with chronic renal diseases (internists, nephrologists and urologists). Moreover, basic scientists such as renal physiologists, renal pathologists and biochemists who want a comprehensive overview of the subject will profit from reading this book | ||
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| genre | (DE-588)4143413-4 Aufsatzsammlung gnd-content |
| genre_facet | Aufsatzsammlung |
| id | DE-604.BV036069375 |
| illustrated | Illustrated |
| indexdate | 2024-12-20T14:06:08Z |
| institution | BVB |
| isbn | 9783318007480 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-018960680 |
| oclc_num | 873639937 |
| open_access_boolean | |
| owner | DE-384 DE-473 DE-BY-UBG DE-703 DE-29 DE-19 DE-BY-UBM DE-91 DE-BY-TUM DE-739 DE-355 DE-BY-UBR DE-20 DE-1102 DE-1028 DE-573 DE-859 DE-M347 DE-1049 DE-92 DE-898 DE-BY-UBR DE-863 DE-BY-FWS DE-862 DE-BY-FWS DE-128 DE-54 DE-22 DE-BY-UBG DE-150 DE-155 DE-BY-UBR DE-521 DE-522 DE-526 DE-12 DE-83 DE-M382 DE-70 DE-578 DE-11 DE-1046 |
| owner_facet | DE-384 DE-473 DE-BY-UBG DE-703 DE-29 DE-19 DE-BY-UBM DE-91 DE-BY-TUM DE-739 DE-355 DE-BY-UBR DE-20 DE-1102 DE-1028 DE-573 DE-859 DE-M347 DE-1049 DE-92 DE-898 DE-BY-UBR DE-863 DE-BY-FWS DE-862 DE-BY-FWS DE-128 DE-54 DE-22 DE-BY-UBG DE-150 DE-155 DE-BY-UBR DE-521 DE-522 DE-526 DE-12 DE-83 DE-M382 DE-70 DE-578 DE-11 DE-1046 |
| physical | 1 Online-Ressource (X, 268 Seiten) Illustrationen, Diagramme |
| psigel | ZDB-1-KEB |
| publishDate | 2001 |
| publishDateSearch | 2001 |
| publishDateSort | 2001 |
| publisher | Karger |
| record_format | marc |
| series | Contributions to nephrology |
| series2 | Contributions to nephrology |
| spellingShingle | The renin-angiotensin system and progression of renal diseases Contributions to nephrology Nephrology Physiology Biochemistry Endocrinology Pathology Urology Renin-Angiotensin-System (DE-588)4177770-0 gnd Pathophysiologie (DE-588)4044898-8 gnd Nierenkrankheit (DE-588)4075399-2 gnd |
| subject_GND | (DE-588)4177770-0 (DE-588)4044898-8 (DE-588)4075399-2 (DE-588)4143413-4 |
| title | The renin-angiotensin system and progression of renal diseases |
| title_alt | The renin angiotensin system and progression of renal diseases |
| title_auth | The renin-angiotensin system and progression of renal diseases |
| title_exact_search | The renin-angiotensin system and progression of renal diseases |
| title_full | The renin-angiotensin system and progression of renal diseases volume editor: Gunter Wolf |
| title_fullStr | The renin-angiotensin system and progression of renal diseases volume editor: Gunter Wolf |
| title_full_unstemmed | The renin-angiotensin system and progression of renal diseases volume editor: Gunter Wolf |
| title_short | The renin-angiotensin system and progression of renal diseases |
| title_sort | the renin angiotensin system and progression of renal diseases |
| topic | Nephrology Physiology Biochemistry Endocrinology Pathology Urology Renin-Angiotensin-System (DE-588)4177770-0 gnd Pathophysiologie (DE-588)4044898-8 gnd Nierenkrankheit (DE-588)4075399-2 gnd |
| topic_facet | Nephrology Physiology Biochemistry Endocrinology Pathology Urology Renin-Angiotensin-System Pathophysiologie Nierenkrankheit Aufsatzsammlung |
| url | https://karger.com/books/book/2393 |
| volume_link | (DE-604)BV039142755 |
| work_keys_str_mv | AT wolfgunter thereninangiotensinsystemandprogressionofrenaldiseases |