Relationship between intracellular glutathione content and dimethylfumarate-induced cytotoxicity in normal human epidermal keratinocytes, human fibroblasts, and human tumor cell lines:
Gespeichert in:
| Beteilige Person: | |
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| Format: | Hochschulschrift/Dissertation Buch |
| Sprache: | Englisch |
| Veröffentlicht: |
2009
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| Schlagwörter: | |
| Links: | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=017684617&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| Umfang: | 43 S. graph. Darst. 21 cm |
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Datensatz im Suchindex
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| adam_text | Titel: Relationship between intracellular glutathione content and dimethylfumarate-induced cytotoxicity in
Autor: Zhou, Qiang
Jahr: 2009
Index
1. Introduction
1.1 Background
1.2 Purpose of the study
5
5
10
11
11
11
11
12
16
2. Materials and Methods
2.1 Cell culture
2.1.1 Cell lines
2 12 Cellculture conditions
2.2 Neutral red assay
2.2.1 Principles of neutral red assay 12
2.2.2 Procedures of neutral red assay 2
2.3 Intracellular GSH assay 14
2.3.1 Principles of intracellular GSH assay I4
2 3.2 Procedures of intracellular GSH assay 14
2.4 BCA protein assay
2.4.1 Principles of BCA protein assay 16
2.4 2 Procedures of BCA protein assay 16
2.5 Statistical analysis 17
3. Results 18
3.1 Neutral red assay 18
3.1.1 Human tumor cell lines 18
3.1.2 Human fibroblasts and NHEK 20
3.1.3 EC5 ) ofDMF in human fibroblasts, NHEK and Mai. Me!.-26 20
3 2 BCA protein assay and intracellular GSH assay 21
3.2.1 BCA protein assay 21
3.2.2 Intracellular GSH assay 21
3 2 3 Intracellular GSH content 22
3.3 Comparison of intracellular GSH content and EC25 23
4. Discussion 24
5. Summary 30
6. References 32
7. Acknowledgements 41
8. Curriculum vitae 42
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| dewey-ones | 616 - Diseases |
| dewey-raw | 616.5 |
| dewey-search | 616.5 |
| dewey-sort | 3616.5 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
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| indexdate | 2024-12-20T13:39:18Z |
| institution | BVB |
| language | English |
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| spellingShingle | Zhou, Qiang 1974- Relationship between intracellular glutathione content and dimethylfumarate-induced cytotoxicity in normal human epidermal keratinocytes, human fibroblasts, and human tumor cell lines |
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| title | Relationship between intracellular glutathione content and dimethylfumarate-induced cytotoxicity in normal human epidermal keratinocytes, human fibroblasts, and human tumor cell lines |
| title_auth | Relationship between intracellular glutathione content and dimethylfumarate-induced cytotoxicity in normal human epidermal keratinocytes, human fibroblasts, and human tumor cell lines |
| title_exact_search | Relationship between intracellular glutathione content and dimethylfumarate-induced cytotoxicity in normal human epidermal keratinocytes, human fibroblasts, and human tumor cell lines |
| title_full | Relationship between intracellular glutathione content and dimethylfumarate-induced cytotoxicity in normal human epidermal keratinocytes, human fibroblasts, and human tumor cell lines vorgelegt von Qiang Zhou |
| title_fullStr | Relationship between intracellular glutathione content and dimethylfumarate-induced cytotoxicity in normal human epidermal keratinocytes, human fibroblasts, and human tumor cell lines vorgelegt von Qiang Zhou |
| title_full_unstemmed | Relationship between intracellular glutathione content and dimethylfumarate-induced cytotoxicity in normal human epidermal keratinocytes, human fibroblasts, and human tumor cell lines vorgelegt von Qiang Zhou |
| title_short | Relationship between intracellular glutathione content and dimethylfumarate-induced cytotoxicity in normal human epidermal keratinocytes, human fibroblasts, and human tumor cell lines |
| title_sort | relationship between intracellular glutathione content and dimethylfumarate induced cytotoxicity in normal human epidermal keratinocytes human fibroblasts and human tumor cell lines |
| topic_facet | Hochschulschrift |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=017684617&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT zhouqiang relationshipbetweenintracellularglutathionecontentanddimethylfumarateinducedcytotoxicityinnormalhumanepidermalkeratinocyteshumanfibroblastsandhumantumorcelllines |