The diffuse endocrine system: from embryogenesis to carcinogenesis ; with 7 tables
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | Englisch |
| Veröffentlicht: |
Jena
Urban & Fischer
2003
|
| Ausgabe: | [Bindeeinh.] |
| Schriftenreihe: | Progress in histochemistry and cytochemistry
38,2 |
| Schlagwörter: | |
| Links: | http://www.gbv.de/dms/hbz/toc/ht013664317.pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=017102186&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| Umfang: | S. 158 - 272 Ill |
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| 245 | 1 | 0 | |a The diffuse endocrine system |b from embryogenesis to carcinogenesis ; with 7 tables |c Luis M. Montuenga ... |
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Datensatz im Suchindex
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| adam_text | Contents
1 Introduction. General aspects of the diffuse endocrine system 163
1.1 Biochemical and cytological traits of endocrine cells 163
1.1.1 Cytological traits of classical and diffuse endocrine cells 163
1.1.2 Processing of regulatory factors in peptide secreting endocrine cells . . 166
1.2 Historical background and terminology of the diffuse endocrine system 168
1.2.1 Discovery and early terminology 168
1.2.2 The introduction of the diffuse endocrine system concept 169
1.2.3 Ultrastructural characterization 169
1.2.4 Immunocytochemical characterization 169
1.2.5 APUD cells 171
1.2.6 Paraneurons 174
1.2.7 Neuroendocrine cells. Diffuse neuroendocrine system 174
1.2.8 Other terms 175
1.3 Basic concepts of the diffuse endocrine system 175
1.3.1 Endocrine versus exocrine mechanisms 175
1.3.2 What is endocrine ? 177
1.3.3 What is diffuse ? 180
1.3.4 Role and secretory mechanisms of DES cells 180
1.3.4.1 Endocrine, paracrine, autocrine mechanisms 180
1.3.4.2 Open and closed cells 181
2 Gastroenteropancreatic (GEP) diffuse endocrine system 183
2.1 General traits and distribution of gastroenteropancreatic endocrine cell
types 183
2.1.1 Classical regulatory substances and endocrine cell types 186
2.1.2 Novel regulatory substances 190
2.2 Ontogeny of DES cells in the gastroenteropancreatic system 193
2.2.1 The endocrine pancreas: a model for the morphogenesis and differentia¬
tion of endocrine system 194
2.2.1.1 Basic helix-loop-helix transcription factors (bHLH) 197
2.2.1.2 Homeoproteins of the LIM family 199
2.2.1.3 Proteins of the paired box (Pax) family 199
2.2.1.4 Homeobox proteins 200
2.2.1.5 Cut homeodomain class proteins 201
2.2.2 Ontogeny of gastrointestinal DES cells 202
2.2.2.1 bHLH factors: Beta2/NeuroD, Hesl and Notch signalling pathway . . 202
2.2.2.2 Proteins of the Pax family: Pax4 and Pax6 203
2.2.2.3 Homeobox proteins: Pdxl and Nkx6.1 203
2.3 Endocrine cell proliferations of the gut 204
2.3.1 Endocrine cell hyperplasia 205
158 • Contents
2.3.2 Carcinoids 206
2.3.3 Mixed endocrine and nonendocrine 208
2.3.4 Molecular aspects of gastrointestinal NE tumors 208
3 Pulmonary diffuse endocrine system 209
3.1 General traits of pulmonary neuroendocrine (PNE) cells 210
3.1.1 Localization 210
3.1.2 Ultrastructure 210
3.1.3 Markers and secretory products 210
3.1.4 Functions of pulmonary NE cells: chemoreception and secretion .... 212
3.2 Ontogeny and differentiation of pulmonary NE cells 217
3.2.1 Role of pulmonary NE cells in lung development 217
3.2.2 Differentiation of pulmonary NE cells 218
3.3 Lung NE hyperplasia and tumors 221
3.3.1 Lung NE hyperplasia 221
3.3.2 Lung NE tumors 224
3.3.2.1 Nomenclature, classification and diagnosis 224
3.3.2.2 Lung NE tumorigenesis: two hypothesis 227
4 Prostatic diffuse endocrine system 232
4.1 General traits of prostate NE cells 233
4.1.1 Morphological features of prostate NE cells 233
4.1.2 Secretory products and markers 233
4.2 Ontogeny of prostate NE cells 237
4.3 Prostate NE tumors 238
4.3.1 NE differentiation and prostatic carcinoma 238
4.3.2 The molecular biology of NE cell differentiation in prostatic carcinoma 240
4.3.3 Models for the study of NE differentiation in prostatic carcinoma . . . 241
5 Concluding remarks 243
6 References 245
|
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| id | DE-604.BV035297252 |
| illustrated | Illustrated |
| indexdate | 2024-12-20T13:27:57Z |
| institution | BVB |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-017102186 |
| oclc_num | 634984197 |
| open_access_boolean | |
| owner | DE-91 DE-BY-TUM DE-578 |
| owner_facet | DE-91 DE-BY-TUM DE-578 |
| physical | S. 158 - 272 Ill |
| publishDate | 2003 |
| publishDateSearch | 2003 |
| publishDateSort | 2003 |
| publisher | Urban & Fischer |
| record_format | marc |
| series | Progress in histochemistry and cytochemistry |
| series2 | Progress in histochemistry and cytochemistry |
| spellingShingle | The diffuse endocrine system from embryogenesis to carcinogenesis ; with 7 tables Progress in histochemistry and cytochemistry Organogenese (DE-588)4266352-0 gnd Endokrinium (DE-588)4152176-6 gnd Carcinogenese (DE-588)4069853-1 gnd |
| subject_GND | (DE-588)4266352-0 (DE-588)4152176-6 (DE-588)4069853-1 |
| title | The diffuse endocrine system from embryogenesis to carcinogenesis ; with 7 tables |
| title_auth | The diffuse endocrine system from embryogenesis to carcinogenesis ; with 7 tables |
| title_exact_search | The diffuse endocrine system from embryogenesis to carcinogenesis ; with 7 tables |
| title_full | The diffuse endocrine system from embryogenesis to carcinogenesis ; with 7 tables Luis M. Montuenga ... |
| title_fullStr | The diffuse endocrine system from embryogenesis to carcinogenesis ; with 7 tables Luis M. Montuenga ... |
| title_full_unstemmed | The diffuse endocrine system from embryogenesis to carcinogenesis ; with 7 tables Luis M. Montuenga ... |
| title_short | The diffuse endocrine system |
| title_sort | the diffuse endocrine system from embryogenesis to carcinogenesis with 7 tables |
| title_sub | from embryogenesis to carcinogenesis ; with 7 tables |
| topic | Organogenese (DE-588)4266352-0 gnd Endokrinium (DE-588)4152176-6 gnd Carcinogenese (DE-588)4069853-1 gnd |
| topic_facet | Organogenese Endokrinium Carcinogenese |
| url | http://www.gbv.de/dms/hbz/toc/ht013664317.pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=017102186&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV000005277 |
| work_keys_str_mv | AT montuengaluism thediffuseendocrinesystemfromembryogenesistocarcinogenesiswith7tables |
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