Verfügbarkeit: The organic chemistry of biological pathways

The organic chemistry of biological pathways:

Gespeichert in:

Bibliographische Detailangaben
Beteiligte Personen:	McMurry, John 1942- (VerfasserIn), Begley, Tadhg P. (VerfasserIn)
Format:	Buch
Sprache:	Englisch
Veröffentlicht:	Englewood, Colo. Roberts and Co. Publ. 2005
Schlagwörter:	Bioquímica orgânica Biosynthèse Chimie bio-organique Metabolismo (fisiologia) Métabolisme aBioorganic chemistry aMetabolism aMetabolism > xphysiology aEnzymes > xmetabolism Stoffwechselphysiologie Organische Chemie Naturstoffchemie Reaktionsmechanismus Stoffwechsel Stoffwechselweg Biochemie
Links:	http://www.loc.gov/catdir/toc/ecip0422/2004020374.html http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=013133628&sequence=000007&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
Beschreibung:	Includes bibliographical references and index
Umfang:	XXI, 490 S. graph. Darst.
ISBN:	0974707716

Internformat

MARC


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500			\|a Includes bibliographical references and index
505	8		\|a Common mechanisms in bioorganic chemistry -- Biomolecules -- Lipid metabolism -- Carbohydrate metabolism -- Amino acid metabolism -- Nucleotide metabolism -- Biosynthesis of some natural products -- A summary of biological transformations.
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Datensatz im Suchindex

DE-BY-TUM_call_number	1002 CHE 801f 2005 A 3127
DE-BY-TUM_katkey	1506634
DE-BY-TUM_location	10
DE-BY-TUM_media_number	040050366355
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adam_text	IMAGE 1 FOREWORD XV PREFACE XVII REVIEWERS XIX THE AUTHORS XXI 1 COMMON MECHANISMS IN BIOLOGICAL CHEMISTRY 1 2 BIOMOLECULES 43 3 LIPID METABOLISM 93 4 CARBOHYDRATE METABOLISM 161 5 AMINO ACID METABOLISM 221 6 NUCLEOTIDE METABOLISM 305 7 BIOSYNTHESIS OF SOME NATURAL PRODUCTS 339 8 A SUMMARY OF BIOLOGICAL TRANSFORMATIONS 409 APPENDIXES 429 A. VISUALIZING PROTEIN STRUCTURES USING THE SWISS PDB VIEWER 429 B. USING THE KEGG AND BRENDA DATABASES 436 C. ANSWERS T O END-OF-CHAPTER PROBLEMS 441 D. ABBREVIATIONS USED IN THIS BOOK 474 INDEX 477 IMAGE 2 FOREWORD XV PREFACE XVII REVIEWERS XIX THE AUTHORS XXI 1 COMMON MECHANISMS IN BIOLOGICAL CHEMISTRY 1 1 . L FUNCTIONAL GROUPS IN BIOLOGICAL CHEMISTRY 3 1.2 ACIDS AND BASES; ELECTROPHILES AND NUCLEOPHILES 6 BRMNSTED-LOWRY ACIDS AND BASES 6 LEWIS ACIDS AND BASES 10 ELECTROPHILES AND NUCLEOPHILES 11 1.3 MECHANISMS: ELECTROPHILIC ADDITION REACTIONS 12 1.4 MECHANISMS: NUCLEOPHILIC SUBSTITUTION REACTIONS 14 1.5 MECHANISMS: NUCLEOPHILIC CARBONYL ADDITION REACTIONS 17 NUCLEOPHILIC ADDITION REACTIONS 18 ALCOHOL FORMATION 20 LMINE (SCHIFF BASE) FORMATION 20 ACETAL FORMATION 22 CONJUGATE (1,4) NUCLEOPHILIC ADDITIONS 24 1.6 MECHANISMS: NUCLEOPHILIC ACYL SUBSTITUTION REACTIONS 26 1.7 MECHANISMS: CARBONYL CONDENSATION REACTIONS 28 1.8 MECHANISMS: ELIMINATION REACTIONS 32 1.9 OXIDATIONS AND REDUCTIONS 34 PROBLEMS 37 2 BIOMOLECULES 43 2.1 CHIRALITY AND BIOLOGICAL CHEMISTRY 44 ENANTIOMERS 45 DIASTEREOMERS, EPIMERS, AND MESO COMPOUNDS 47 PROCHIRALITY 50 2.2 BIOMOLECULES: LIPIDS 52 TRIACYLGLYCEROLS 52 OTHER LIPIDS: TERPENOIDS, STEROIDS, AND PROSTAGLANDINS 54 IMAGE 3 X CONTENTS 2.3 BIOMOLECULES: CARBOHYDRATES 56 CARBOHYDRATE STEREOCHEMISTRY 57 MONOSACCHARIDE ANOMERS 58 DISACCHARIDES AND POLYSACCHARIDES 61 DEOXY SUGARS AND AMINO SUGARS 62 2.4 BIOMOLECULES: AMINO ACIDS, PEPTIDES, AND PROTEINS 63 AMINO ACIDS 64 PEPTIDES AND PROTEINS 68 2.5 BIOMOLECULES: NUCLEIC ACIDS 72 DNA: DEOXYRIBONUCLEIC ACID 75 RNA: RIBONUCLEIC ACID 76 2.6 BIOMOLECULES: ENZYMES, COENZYMES, AND COUPLED REACTIONS 77 ENZYMES 77 COENZYMES 80 COUPLED REACTIONS AND HIGH-ENERGY COMPOUNDS 83 PROBLEMS 86 3 LIPID METABOLISM 93 3.1 DIGESTION AND TRANSPORT OF TRIACYLGLYCEROLS 94 TRIACYLGLYCEROL HYDROLYSIS 95 A BRIEF NOTE ABOUT VISUALIZING ENZYME STRUCTURES 97 TRIACYLGLYCEROL RESYNTHESIS 99 3.2 TRIACYLGLYCEROL CATABOLISM: THE FATE OF GLYCEROL 102 3.3 TRIACYLGLYCEROL CATABOLISM: FATTY-ACID OXIDATION 106 3.4 FATTY-ACID BIOSYNTHESIS 11 5 3.5 TERPENOID BIOSYNTHESIS 125 THE MEVALONATE PATHWAY TO LSOPENTENYL DIPHOSPHATE 126 THE DEOXYXYLULOSE PHOSPHATE PATHWAY T O LSOPENTENYL DIPHOSPHATE 132 CONVERSION OF LSOPENTENYL DIPHOSPHATE T O TERPENOIDS 139 3.6 STEROID BIOSYNTHESIS 144 CONVERSION OF FARNESYL DIPHOSPHATE T O SQUALENE 144 CONVERSION OF SQUALENE T O LANOSTEROL 148 REFERENCES 153 PROBLEMS 156 IMAGE 4 CONTENTS XI 4 CARBOHYDRATE METABOLISM 161 4.1 DIGESTION AND HYDROLYSIS OF COMPLEX CARBOHYDRATES 162 4.2 GLUCOSE CATABOLISM: GLYCOLYSIS L64 4.3 TRANSFORMATIONS OF PYRUVATE L 7 8 CONVERSION OF PYRUVATE TO LACTATE 179 CONVERSION OF PYRUVATE T O ETHANOL 179 CONVERSION OF PYRUVATE T O ACETYL COA L81 4.4 THE CITRIC ACID CYCLE 185 4.5 GLUCOSE BIOSYNTHESIS: GLUCONEOGENESIS 193 4.6 THE PENTOSE PHOSPHATE PATHWAY 203 4.7 PHOTOSYNTHESIS: THE REDUCTIVE PENTOSE PHOSPHATE (CALVIN)CYCLE 211 REFERENCES 21 6 PROBLEMS 218 5 AMINO ACID METABOLISM 221 5.1 DEAMINATION OF AMINO ACIDS 223 TRANSAMINATION OF AMINO ACIDS 223 OXIDATIVE DEAMINATION OF GLUTAMATE 227 5.2 THE UREA CYCLE 228 5.3 CATABOLISM OF AMINO ACID CARBON CHAINS 232 ALANINE, SERINE, GLYCINE, CYSTEINE, THREONINE, AND TRYPTOPHAN 234 A BRIEF NOTE ABOUT OXIDATION STATES IN IRON COMPLEXES 241 A BRIEF NOTE ABOUT PLP REACTIONS 251 ASPARAGINE AND ASPARTATE 252 GLUTAMINE, GLUTAMATE, ARGININE, HISTIDINE, AND PROLINE 252 VALINE, ISOLEUCINE, AND LEUCINE 255 METHIONINE 259 LYSINE 264 PHENYLALANINE AND TYROSINE 265 5.4 BIOSYNTHESIS OF NONESSENTIAL AMINO ACIDS 271 ALANINE, ASPARTATE, GLUTAMATE, ASPARAGINE, GLUTAMINE, ARGININE, AND PROLINE 273 SERINE, CYSTEINE, AND GLYCINE 274 IMAGE 5 XII CONTENTS 5.5 BIOSYNTHESIS OF ESSENTIAL AMINO ACIDS 276 LYSINE, METHIONINE, AND THREONINE 276 ISOLEUCINE, VALINE, AND LEUCINE 284 TRYPTOPHAN, PHENYLALANINE, AND TYROSINE 286 HISTIDINE 295 REFERENCES 297 PROBLEMS 301 6 NUCLEOTIDE METABOLISM 305 6.1 NUCLEOTIDE CATABOLISM 307 PYRIMIDINES: CYTIDINE, URIDINE, AND THYMIDINE 307 PURINES: ADENOSINE AND GUANOSINE 31 1 6.2 BIOSYNTHESIS OF PYRIMIDINE RI BONUCLEOTIDES 31 3 URIDINE MONOPHOSPHATE 313 CYTIDINE TRIPHOSPHATE 318 6.3 BIOSYNTHESIS OF PURINE RIBONUCLEOTIDES 319 LNOSINE MONOPHOSPHATE 319 ADENOSINE MONOPHOSPHATE AND GUANOSINE MONOPHOSPHATE 325 6.4 BIOSYNTHESIS OF DEOXYRIBONUCLEOTIDES 327 DEOXYADENOSINE, DEOXYGUANOSINE, DEOXYCYTIDINE, AND DEOXYURIDINE DIPHOSPHATES 327 THYMIDINE MONOPHOSPHATE 329 REFERENCES 332 PROBLEMS 334 7 BIOSYNTHESIS OF SOME NATURAL PRODUCTS 339 7.1 BIOSYNTHESIS OF PENICILLINS AND CEPHALOSPORINS 342 PENICILLINS 344 CEPHALOSPORINS 349 7.2 BIOSYNTHESIS OF MORPHINE 352 7.3 BIOSYNTHESIS OF PROSTAGLANDINS AND OTHER EICOSANOIDS 363 7.4 BIOSYNTHESIS OF ERYTHROMYCIN 369 IMAGE 6 CONTENTS XIII 7.5 BIOSYNTHESIS OF COENZYME BI2 AND OTHER TETRAPYRROLES 379 URO GEN 1 1 1 380 HEME 384 COENZYME BI2 387 REFERENCES 400 PROBLEMS 403 8 A SUMMARY OF BIOLOGICAL TRANSFORMATIONS 409 HYDROLYSES, ESTERIFICATIONS, THIOESTERIFICATIONS, AND AMIDATIONS 409 CARBONYL CONDENSATIONS 41 1 CARBOXYLATIONS AND DECARBOXYLATIONS 41 3 AMINATIONS AND DEAMINATIONS 41 6 L-CARBON TRANSFERS 417 REARRANGEMENTS 41 9 LSOMERIZATIONS AND EPIMERIZATIONS 420 OXIDATIONS AND REDUCTIONS OF CARBONYL COMPOUNDS 421 HYDROXYLATIONS AND OTHER OXIDATIONS VIA METAL COMPLEXES 424 APPENDIXES 429 A. VISUALIZING PROTEIN STRUCTURES USING THE SWISS PDB VIEWER 429 B. USING THE KEGG AND BRENDA DATABASES 436 C. ANSWERS T O END-OF-CHAPTER PROBLEMS 441 D. ABBREVIATIONS USED IN THIS BOOK 474 INDEX 477
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author	McMurry, John 1942- Begley, Tadhg P.
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contents	Common mechanisms in bioorganic chemistry -- Biomolecules -- Lipid metabolism -- Carbohydrate metabolism -- Amino acid metabolism -- Nucleotide metabolism -- Biosynthesis of some natural products -- A summary of biological transformations.
ctrlnum	(OCoLC)56405024 (DE-599)BVBBV019808158
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id	DE-604.BV019808158
illustrated	Illustrated
indexdate	2024-12-20T12:06:19Z
institution	BVB
isbn	0974707716
language	English
lccn	2004020374
oai_aleph_id	oai:aleph.bib-bvb.de:BVB01-013133628
oclc_num	56405024
open_access_boolean
owner	DE-M49 DE-BY-TUM
owner_facet	DE-M49 DE-BY-TUM
physical	XXI, 490 S. graph. Darst.
publishDate	2005
publishDateSearch	2005
publishDateSort	2005
publisher	Roberts and Co. Publ.
record_format	marc
spellingShingle	McMurry, John 1942- Begley, Tadhg P. The organic chemistry of biological pathways Common mechanisms in bioorganic chemistry -- Biomolecules -- Lipid metabolism -- Carbohydrate metabolism -- Amino acid metabolism -- Nucleotide metabolism -- Biosynthesis of some natural products -- A summary of biological transformations. Bioquímica orgânica larpcal Biosynthèse rasuqam Chimie bio-organique Chimie bio-organique rasuqam Metabolismo (fisiologia) larpcal Métabolisme Métabolisme rasuqam aBioorganic chemistry aMetabolism aMetabolism xphysiology aEnzymes xmetabolism Stoffwechselphysiologie (DE-588)4183413-6 gnd Organische Chemie (DE-588)4043793-0 gnd Naturstoffchemie (DE-588)4171332-1 gnd Reaktionsmechanismus (DE-588)4177123-0 gnd Stoffwechsel (DE-588)4057699-1 gnd Stoffwechselweg (DE-588)4240505-1 gnd Biochemie (DE-588)4006777-4 gnd
subject_GND	(DE-588)4183413-6 (DE-588)4043793-0 (DE-588)4171332-1 (DE-588)4177123-0 (DE-588)4057699-1 (DE-588)4240505-1 (DE-588)4006777-4
title	The organic chemistry of biological pathways
title_auth	The organic chemistry of biological pathways
title_exact_search	The organic chemistry of biological pathways
title_full	The organic chemistry of biological pathways John E. McMurry, Tadhg P. Begley
title_fullStr	The organic chemistry of biological pathways John E. McMurry, Tadhg P. Begley
title_full_unstemmed	The organic chemistry of biological pathways John E. McMurry, Tadhg P. Begley
title_short	The organic chemistry of biological pathways
title_sort	the organic chemistry of biological pathways
topic	Bioquímica orgânica larpcal Biosynthèse rasuqam Chimie bio-organique Chimie bio-organique rasuqam Metabolismo (fisiologia) larpcal Métabolisme Métabolisme rasuqam aBioorganic chemistry aMetabolism aMetabolism xphysiology aEnzymes xmetabolism Stoffwechselphysiologie (DE-588)4183413-6 gnd Organische Chemie (DE-588)4043793-0 gnd Naturstoffchemie (DE-588)4171332-1 gnd Reaktionsmechanismus (DE-588)4177123-0 gnd Stoffwechsel (DE-588)4057699-1 gnd Stoffwechselweg (DE-588)4240505-1 gnd Biochemie (DE-588)4006777-4 gnd
topic_facet	Bioquímica orgânica Biosynthèse Chimie bio-organique Metabolismo (fisiologia) Métabolisme aBioorganic chemistry aMetabolism aMetabolism xphysiology aEnzymes xmetabolism Stoffwechselphysiologie Organische Chemie Naturstoffchemie Reaktionsmechanismus Stoffwechsel Stoffwechselweg Biochemie
url	http://www.loc.gov/catdir/toc/ecip0422/2004020374.html http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=013133628&sequence=000007&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
work_keys_str_mv	AT mcmurryjohn theorganicchemistryofbiologicalpathways AT begleytadhgp theorganicchemistryofbiologicalpathways

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