Microfluidics and nanotechnology: biosensing to the single molecule limit
"Preface Microtechnology and more recent nanotechnology methods have enabled the fabrication of a wide variety of new chemical and biological sensors. These sensors demonstrate exquisite sensitivity and low limits of detection, enabling exploration of new scientific frontiers. In particular, th...
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Weitere beteiligte Personen: | , |
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Format: | Elektronisch E-Book |
Sprache: | Englisch |
Veröffentlicht: |
Boca Raton
CRC Press/Taylor & Francis Group
2014
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Schriftenreihe: | Devices, Circuits, and Systems
|
Schlagwörter: | |
Links: | https://learning.oreilly.com/library/view/-/9781466594906/?ar |
Zusammenfassung: | "Preface Microtechnology and more recent nanotechnology methods have enabled the fabrication of a wide variety of new chemical and biological sensors. These sensors demonstrate exquisite sensitivity and low limits of detection, enabling exploration of new scientific frontiers. In particular, the novel physics that emerges at small length scales allows parallel, mass-fabricated sensors for detection to both single-cell and single-molecule limits. Stochastic differences between individual cells and molecules have been shown to play important roles in larger biological systems, and these novel sensors have begun to test and elucidate these effects. This book focuses on the combination of soft materials like elastomers and other polymers with materials like semiconductors, metals, and glass to form integrated detection systems for biological and chemical targets. Microfluidic advances in this arena include systems for forming and analyzing tiny droplets (so-called droplet microfluidics); the combination of electrostatic and dielectrics to manipulate droplets on the microscale; miniaturized separation systems, including electrophoresis, for detecting a wide range of genetic targets from single cells; and novel optical and mechanical detection methods at the single-cell and single-molecule scales. This book represents a snapshot of the state of the art from the world's leading microfluidics and nanotechnology laboratories. The combination of different materials at both of these length scales is driving a powerful new set of scientific inquiries that have to date been impossible to address using other technologies. The book is arranged in two major sections. In Part I, the authors discuss a number of unique detection technologies"-- |
Beschreibung: | Includes bibliographical references and index. - Print version record |
Umfang: | 1 Online-Ressource (xvi, 274 Seiten) illustrations. |
ISBN: | 9781466594913 1466594918 146659490X 9781466594906 9781315215594 1315215594 9781351822794 1351822799 |
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520 | |a "Preface Microtechnology and more recent nanotechnology methods have enabled the fabrication of a wide variety of new chemical and biological sensors. These sensors demonstrate exquisite sensitivity and low limits of detection, enabling exploration of new scientific frontiers. In particular, the novel physics that emerges at small length scales allows parallel, mass-fabricated sensors for detection to both single-cell and single-molecule limits. Stochastic differences between individual cells and molecules have been shown to play important roles in larger biological systems, and these novel sensors have begun to test and elucidate these effects. This book focuses on the combination of soft materials like elastomers and other polymers with materials like semiconductors, metals, and glass to form integrated detection systems for biological and chemical targets. Microfluidic advances in this arena include systems for forming and analyzing tiny droplets (so-called droplet microfluidics); the combination of electrostatic and dielectrics to manipulate droplets on the microscale; miniaturized separation systems, including electrophoresis, for detecting a wide range of genetic targets from single cells; and novel optical and mechanical detection methods at the single-cell and single-molecule scales. This book represents a snapshot of the state of the art from the world's leading microfluidics and nanotechnology laboratories. The combination of different materials at both of these length scales is driving a powerful new set of scientific inquiries that have to date been impossible to address using other technologies. The book is arranged in two major sections. In Part I, the authors discuss a number of unique detection technologies"-- | ||
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illustrated | Illustrated |
indexdate | 2025-01-17T11:21:19Z |
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spelling | Microfluidics and nanotechnology biosensing to the single molecule limit edited by Eric Lagally, managing editor Krzysztof Iniewski Boca Raton CRC Press/Taylor & Francis Group 2014 ©2014 ©20 1 Online-Ressource (xvi, 274 Seiten) illustrations. Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Devices, Circuits, and Systems Includes bibliographical references and index. - Print version record "Preface Microtechnology and more recent nanotechnology methods have enabled the fabrication of a wide variety of new chemical and biological sensors. These sensors demonstrate exquisite sensitivity and low limits of detection, enabling exploration of new scientific frontiers. In particular, the novel physics that emerges at small length scales allows parallel, mass-fabricated sensors for detection to both single-cell and single-molecule limits. Stochastic differences between individual cells and molecules have been shown to play important roles in larger biological systems, and these novel sensors have begun to test and elucidate these effects. This book focuses on the combination of soft materials like elastomers and other polymers with materials like semiconductors, metals, and glass to form integrated detection systems for biological and chemical targets. Microfluidic advances in this arena include systems for forming and analyzing tiny droplets (so-called droplet microfluidics); the combination of electrostatic and dielectrics to manipulate droplets on the microscale; miniaturized separation systems, including electrophoresis, for detecting a wide range of genetic targets from single cells; and novel optical and mechanical detection methods at the single-cell and single-molecule scales. This book represents a snapshot of the state of the art from the world's leading microfluidics and nanotechnology laboratories. The combination of different materials at both of these length scales is driving a powerful new set of scientific inquiries that have to date been impossible to address using other technologies. The book is arranged in two major sections. In Part I, the authors discuss a number of unique detection technologies"-- Biosensors Biomolecules Cytochemistry Microfluidics Industrial applications Molecular recognition Nanofluids Microfluidics Nanotechnology Biosensing Techniques Histocytochemistry Biocapteurs Biomolécules Cytochimie Microfluidique ; Applications industrielles Reconnaissance moléculaire Nanofluides Microfluidique Nanotechnologie MEDICAL ; Biotechnology SCIENCE ; Chemistry ; Analytic TECHNOLOGY & ENGINEERING ; Sensors SCIENCE ; Life Sciences ; Biochemistry Health & Biological Sciences Biomedical Engineering Lagally, Eric HerausgeberIn edt Iniewski, Krzysztof 1960- HerausgeberIn edt 9781466594906 Erscheint auch als Druck-Ausgabe 9781466594906 |
spellingShingle | Microfluidics and nanotechnology biosensing to the single molecule limit Biosensors Biomolecules Cytochemistry Microfluidics Industrial applications Molecular recognition Nanofluids Microfluidics Nanotechnology Biosensing Techniques Histocytochemistry Biocapteurs Biomolécules Cytochimie Microfluidique ; Applications industrielles Reconnaissance moléculaire Nanofluides Microfluidique Nanotechnologie MEDICAL ; Biotechnology SCIENCE ; Chemistry ; Analytic TECHNOLOGY & ENGINEERING ; Sensors SCIENCE ; Life Sciences ; Biochemistry Health & Biological Sciences Biomedical Engineering |
title | Microfluidics and nanotechnology biosensing to the single molecule limit |
title_auth | Microfluidics and nanotechnology biosensing to the single molecule limit |
title_exact_search | Microfluidics and nanotechnology biosensing to the single molecule limit |
title_full | Microfluidics and nanotechnology biosensing to the single molecule limit edited by Eric Lagally, managing editor Krzysztof Iniewski |
title_fullStr | Microfluidics and nanotechnology biosensing to the single molecule limit edited by Eric Lagally, managing editor Krzysztof Iniewski |
title_full_unstemmed | Microfluidics and nanotechnology biosensing to the single molecule limit edited by Eric Lagally, managing editor Krzysztof Iniewski |
title_short | Microfluidics and nanotechnology |
title_sort | microfluidics and nanotechnology biosensing to the single molecule limit |
title_sub | biosensing to the single molecule limit |
topic | Biosensors Biomolecules Cytochemistry Microfluidics Industrial applications Molecular recognition Nanofluids Microfluidics Nanotechnology Biosensing Techniques Histocytochemistry Biocapteurs Biomolécules Cytochimie Microfluidique ; Applications industrielles Reconnaissance moléculaire Nanofluides Microfluidique Nanotechnologie MEDICAL ; Biotechnology SCIENCE ; Chemistry ; Analytic TECHNOLOGY & ENGINEERING ; Sensors SCIENCE ; Life Sciences ; Biochemistry Health & Biological Sciences Biomedical Engineering |
topic_facet | Biosensors Biomolecules Cytochemistry Microfluidics Industrial applications Molecular recognition Nanofluids Microfluidics Nanotechnology Biosensing Techniques Histocytochemistry Biocapteurs Biomolécules Cytochimie Microfluidique ; Applications industrielles Reconnaissance moléculaire Nanofluides Microfluidique Nanotechnologie MEDICAL ; Biotechnology SCIENCE ; Chemistry ; Analytic TECHNOLOGY & ENGINEERING ; Sensors SCIENCE ; Life Sciences ; Biochemistry Health & Biological Sciences Biomedical Engineering |
work_keys_str_mv | AT lagallyeric microfluidicsandnanotechnologybiosensingtothesinglemoleculelimit AT iniewskikrzysztof microfluidicsandnanotechnologybiosensingtothesinglemoleculelimit |