Alzheimer's disease drug development: research and development ecosystem
Alzheimer's Disease (AD) is a growing global public health challenge. The development of new therapies is urgently needed, and a complex ecosystem of organizations has grown to facilitate AD drug discovery and development. Masterfully collating information on the drug development ecosystem, thi...
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| Weitere beteiligte Personen: | , , |
|---|---|
| Format: | E-Book |
| Sprache: | Englisch |
| Veröffentlicht: |
Cambridge
Cambridge University Press
2022
|
| Schriftenreihe: | Cambridge medicine
|
| Links: | https://doi.org/10.1017/9781108975759 |
| Zusammenfassung: | Alzheimer's Disease (AD) is a growing global public health challenge. The development of new therapies is urgently needed, and a complex ecosystem of organizations has grown to facilitate AD drug discovery and development. Masterfully collating information on the drug development ecosystem, this book emphasizes the contributions of each aspect in the pipeline with a uniform approach to chapters, enabling readers to access relevant information quickly. Topics covered include the use of non-clinical laboratory studies, biomarker development, artificial intelligence, design and management of clinical trials, and funding and financing models. Also discussed is the critical role of advocacy fundraising for drug development. With the approval of aducanumab, the function of the ecosystem has become apparent. This is a definitive overview of how the ecosystem works in transferring an AD drug from its discovery in the laboratory through clinical trial testing to regulatory review and eventual marketing. |
| Umfang: | 1 Online-Ressource (xx, 554 Seiten) |
| ISBN: | 9781108975759 |
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| spelling | Alzheimer's disease drug development research and development ecosystem edited by Jeffrey Cummings, Jefferson Kinney, Howard Fillit Cambridge Cambridge University Press 2022 1 Online-Ressource (xx, 554 Seiten) txt c cr Cambridge medicine Alzheimer's Disease (AD) is a growing global public health challenge. The development of new therapies is urgently needed, and a complex ecosystem of organizations has grown to facilitate AD drug discovery and development. Masterfully collating information on the drug development ecosystem, this book emphasizes the contributions of each aspect in the pipeline with a uniform approach to chapters, enabling readers to access relevant information quickly. Topics covered include the use of non-clinical laboratory studies, biomarker development, artificial intelligence, design and management of clinical trials, and funding and financing models. Also discussed is the critical role of advocacy fundraising for drug development. With the approval of aducanumab, the function of the ecosystem has become apparent. This is a definitive overview of how the ecosystem works in transferring an AD drug from its discovery in the laboratory through clinical trial testing to regulatory review and eventual marketing. Cummings, Jeffrey L. 1948- Fillit, Howard Kinney, Jefferson W. 1971- Erscheint auch als Druck-Ausgabe 9781108838665 |
| spellingShingle | Alzheimer's disease drug development research and development ecosystem |
| title | Alzheimer's disease drug development research and development ecosystem |
| title_auth | Alzheimer's disease drug development research and development ecosystem |
| title_exact_search | Alzheimer's disease drug development research and development ecosystem |
| title_full | Alzheimer's disease drug development research and development ecosystem edited by Jeffrey Cummings, Jefferson Kinney, Howard Fillit |
| title_fullStr | Alzheimer's disease drug development research and development ecosystem edited by Jeffrey Cummings, Jefferson Kinney, Howard Fillit |
| title_full_unstemmed | Alzheimer's disease drug development research and development ecosystem edited by Jeffrey Cummings, Jefferson Kinney, Howard Fillit |
| title_short | Alzheimer's disease drug development |
| title_sort | alzheimer s disease drug development research and development ecosystem |
| title_sub | research and development ecosystem |
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