Clinical Use of Antibodies: Tumours, infection, infarction, rejection and in the diagnosis of AIDS
It was at Frankfurt/Mainin 1899 that Paul Ehrlich first expounded his famous "site-chain theory" -which described the basic immunological principal of antibody-antigen interactio- on the occasion of the opening of the Institute for Experimental Therapeutics (which was later named after him...
Gespeichert in:
Weitere beteiligte Personen: | , , , |
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Format: | Elektronisch E-Book |
Sprache: | Englisch |
Veröffentlicht: |
Dordrecht
Springer Netherlands
1991
|
Schriftenreihe: | Developments in Nuclear Medicine
19 |
Schlagwörter: | |
Links: | https://doi.org/10.1007/978-94-011-3516-0 https://doi.org/10.1007/978-94-011-3516-0 |
Zusammenfassung: | It was at Frankfurt/Mainin 1899 that Paul Ehrlich first expounded his famous "site-chain theory" -which described the basic immunological principal of antibody-antigen interactio- on the occasion of the opening of the Institute for Experimental Therapeutics (which was later named after him). Nearly 100 years have passed since, and in retrospect it can be said that the "Ehrlich Era" (first steps in immunology "Magic Bullet" concept) and the "Behring Era" (detection of antibodies and serum therapy) formed the essential basis in the development of immunology. Niels K. Jerne, the former director of the Paul Ehrlich Institute in Frankfurt/Main received, together with Georges Kohler and Cesar Milstein, the Nobel Prize in Medicine 1984. These late successors of Ehrlich and Behring first described the hybridoma technology (in 1975) which enabled one of the most important and revolutionary technological innovations in the field of immunology -the production of monoclonal antibodies. It happens that, the time of the publication of this book, just a decade has passed since the first use of radiolabelled monoclonal antibodies in man (by the Lausanne Group). Over these 10 years a tremendous progress has taken place in the field of immunoscintigraphy:A large panel of highly specific monoclonal antibodies against tumour-associated antigens as well as normal cell compounds have been developed. Enormous progress has been made in the field of radiolabelling -from iodine-131 to technetium-99mor even positron-emittingradionuclides, e. g. iodine-124 |
Umfang: | 1 Online-Ressource (X, 185 p) |
ISBN: | 9789401135160 |
DOI: | 10.1007/978-94-011-3516-0 |
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520 | |a It was at Frankfurt/Mainin 1899 that Paul Ehrlich first expounded his famous "site-chain theory" -which described the basic immunological principal of antibody-antigen interactio- on the occasion of the opening of the Institute for Experimental Therapeutics (which was later named after him). Nearly 100 years have passed since, and in retrospect it can be said that the "Ehrlich Era" (first steps in immunology "Magic Bullet" concept) and the "Behring Era" (detection of antibodies and serum therapy) formed the essential basis in the development of immunology. Niels K. Jerne, the former director of the Paul Ehrlich Institute in Frankfurt/Main received, together with Georges Kohler and Cesar Milstein, the Nobel Prize in Medicine 1984. These late successors of Ehrlich and Behring first described the hybridoma technology (in 1975) which enabled one of the most important and revolutionary technological innovations in the field of immunology -the production of monoclonal antibodies. It happens that, the time of the publication of this book, just a decade has passed since the first use of radiolabelled monoclonal antibodies in man (by the Lausanne Group). Over these 10 years a tremendous progress has taken place in the field of immunoscintigraphy:A large panel of highly specific monoclonal antibodies against tumour-associated antigens as well as normal cell compounds have been developed. Enormous progress has been made in the field of radiolabelling -from iodine-131 to technetium-99mor even positron-emittingradionuclides, e. g. iodine-124 | ||
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Datensatz im Suchindex
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any_adam_object | |
author2 | Baum, Richard P. Cox, Peter H. Hör, Gustav Buraggi, Gian Luigi |
author2_role | edt edt edt edt |
author2_variant | r p b rp rpb p h c ph phc g h gh g l b gl glb |
author_facet | Baum, Richard P. Cox, Peter H. Hör, Gustav Buraggi, Gian Luigi |
building | Verbundindex |
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collection | ZDB-2-SME |
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discipline | Medizin |
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institution | BVB |
isbn | 9789401135160 |
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spelling | Clinical Use of Antibodies Tumours, infection, infarction, rejection and in the diagnosis of AIDS edited by Richard P. Baum, Peter H. Cox, Gustav Hör, Gian Luigi Buraggi Dordrecht Springer Netherlands 1991 1 Online-Ressource (X, 185 p) txt rdacontent c rdamedia cr rdacarrier Developments in Nuclear Medicine 19 It was at Frankfurt/Mainin 1899 that Paul Ehrlich first expounded his famous "site-chain theory" -which described the basic immunological principal of antibody-antigen interactio- on the occasion of the opening of the Institute for Experimental Therapeutics (which was later named after him). Nearly 100 years have passed since, and in retrospect it can be said that the "Ehrlich Era" (first steps in immunology "Magic Bullet" concept) and the "Behring Era" (detection of antibodies and serum therapy) formed the essential basis in the development of immunology. Niels K. Jerne, the former director of the Paul Ehrlich Institute in Frankfurt/Main received, together with Georges Kohler and Cesar Milstein, the Nobel Prize in Medicine 1984. These late successors of Ehrlich and Behring first described the hybridoma technology (in 1975) which enabled one of the most important and revolutionary technological innovations in the field of immunology -the production of monoclonal antibodies. It happens that, the time of the publication of this book, just a decade has passed since the first use of radiolabelled monoclonal antibodies in man (by the Lausanne Group). Over these 10 years a tremendous progress has taken place in the field of immunoscintigraphy:A large panel of highly specific monoclonal antibodies against tumour-associated antigens as well as normal cell compounds have been developed. Enormous progress has been made in the field of radiolabelling -from iodine-131 to technetium-99mor even positron-emittingradionuclides, e. g. iodine-124 Nuclear Medicine Diagnostic Radiology Oncology Nuclear medicine Radiology, Medical Oncology Diagnostik (DE-588)4113303-1 gnd rswk-swf Monoklonaler Antikörper (DE-588)4040094-3 gnd rswk-swf Therapie (DE-588)4059798-2 gnd rswk-swf 1\p (DE-588)1071861417 Konferenzschrift 1990 Frankfurt am Main gnd-content Monoklonaler Antikörper (DE-588)4040094-3 s Diagnostik (DE-588)4113303-1 s 2\p DE-604 Therapie (DE-588)4059798-2 s 3\p DE-604 Baum, Richard P. edt Cox, Peter H. edt Hör, Gustav edt Buraggi, Gian Luigi edt Erscheint auch als Druck-Ausgabe 9780792314240 Erscheint auch als Druck-Ausgabe 9789401055550 Erscheint auch als Druck-Ausgabe 9789401135177 https://doi.org/10.1007/978-94-011-3516-0 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 3\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
spellingShingle | Clinical Use of Antibodies Tumours, infection, infarction, rejection and in the diagnosis of AIDS Nuclear Medicine Diagnostic Radiology Oncology Nuclear medicine Radiology, Medical Oncology Diagnostik (DE-588)4113303-1 gnd Monoklonaler Antikörper (DE-588)4040094-3 gnd Therapie (DE-588)4059798-2 gnd |
subject_GND | (DE-588)4113303-1 (DE-588)4040094-3 (DE-588)4059798-2 (DE-588)1071861417 |
title | Clinical Use of Antibodies Tumours, infection, infarction, rejection and in the diagnosis of AIDS |
title_auth | Clinical Use of Antibodies Tumours, infection, infarction, rejection and in the diagnosis of AIDS |
title_exact_search | Clinical Use of Antibodies Tumours, infection, infarction, rejection and in the diagnosis of AIDS |
title_full | Clinical Use of Antibodies Tumours, infection, infarction, rejection and in the diagnosis of AIDS edited by Richard P. Baum, Peter H. Cox, Gustav Hör, Gian Luigi Buraggi |
title_fullStr | Clinical Use of Antibodies Tumours, infection, infarction, rejection and in the diagnosis of AIDS edited by Richard P. Baum, Peter H. Cox, Gustav Hör, Gian Luigi Buraggi |
title_full_unstemmed | Clinical Use of Antibodies Tumours, infection, infarction, rejection and in the diagnosis of AIDS edited by Richard P. Baum, Peter H. Cox, Gustav Hör, Gian Luigi Buraggi |
title_short | Clinical Use of Antibodies |
title_sort | clinical use of antibodies tumours infection infarction rejection and in the diagnosis of aids |
title_sub | Tumours, infection, infarction, rejection and in the diagnosis of AIDS |
topic | Nuclear Medicine Diagnostic Radiology Oncology Nuclear medicine Radiology, Medical Oncology Diagnostik (DE-588)4113303-1 gnd Monoklonaler Antikörper (DE-588)4040094-3 gnd Therapie (DE-588)4059798-2 gnd |
topic_facet | Nuclear Medicine Diagnostic Radiology Oncology Nuclear medicine Radiology, Medical Oncology Diagnostik Monoklonaler Antikörper Therapie Konferenzschrift 1990 Frankfurt am Main |
url | https://doi.org/10.1007/978-94-011-3516-0 |
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