Geriatric Medicine: An Evidence-Based Approach
Since the publication of the third edition of Geriatric Medicine,extraordinary advances have occurred in the science of aging and the potential for biomedical research to give us answers to many, if not most, of the age-related disorders that threaten the quality of life in older years. At the most...
Gespeichert in:
Beteiligte Personen: | , , , |
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Format: | Elektronisch E-Book |
Sprache: | Englisch |
Veröffentlicht: |
New York, NY
Springer New York
2003
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Ausgabe: | Fourth Edition |
Schlagwörter: | |
Links: | https://doi.org/10.1007/b97639 https://doi.org/10.1007/b97639 |
Zusammenfassung: | Since the publication of the third edition of Geriatric Medicine,extraordinary advances have occurred in the science of aging and the potential for biomedical research to give us answers to many, if not most, of the age-related disorders that threaten the quality of life in older years. At the most basic level, the successful mapping of the human genome was declared complete in the fall of 2000. Understanding the map of the human genome is as important as understanding the map of genomes of important laboratory species, ranging from the microscopic worms and fruit?ies used in most classic genetic studies to rodents such as laboratory mice, and eventually to primates, on which much of the research on the aging human brain is done. The genetic maps of all of these species,including our own,does not answer clinical questions,but it does open the door to dramatic, rapid, and ef?cient answers to questions about the genetic polymorphisms related to diseases in humans. The telomerase story also unfolded since the third edition. Telomerase is an enzyme responsible for maintaining the telomeres—the redundant DNA portions at the end of chromosomes—whose shortening seems to be linked directly to cell senescence,ap- tosis,and the control over cell death,which,at the level of the individual cell,seems to be linked to the decline of organ function and eventually aging and death within the org- ism |
Umfang: | 1 Online-Ressource (L, 1318 p) |
ISBN: | 9780387226217 |
DOI: | 10.1007/b97639 |
Internformat
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520 | |a Since the publication of the third edition of Geriatric Medicine,extraordinary advances have occurred in the science of aging and the potential for biomedical research to give us answers to many, if not most, of the age-related disorders that threaten the quality of life in older years. At the most basic level, the successful mapping of the human genome was declared complete in the fall of 2000. Understanding the map of the human genome is as important as understanding the map of genomes of important laboratory species, ranging from the microscopic worms and fruit?ies used in most classic genetic studies to rodents such as laboratory mice, and eventually to primates, on which much of the research on the aging human brain is done. The genetic maps of all of these species,including our own,does not answer clinical questions,but it does open the door to dramatic, rapid, and ef?cient answers to questions about the genetic polymorphisms related to diseases in humans. The telomerase story also unfolded since the third edition. Telomerase is an enzyme responsible for maintaining the telomeres—the redundant DNA portions at the end of chromosomes—whose shortening seems to be linked directly to cell senescence,ap- tosis,and the control over cell death,which,at the level of the individual cell,seems to be linked to the decline of organ function and eventually aging and death within the org- ism | ||
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Datensatz im Suchindex
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author | Cassel, Christine K. Leipzig, Rosanne M. Cohen, Harvey Jay Larson, Eric B. |
author_facet | Cassel, Christine K. Leipzig, Rosanne M. Cohen, Harvey Jay Larson, Eric B. |
author_role | aut aut aut aut |
author_sort | Cassel, Christine K. |
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dewey-full | 610 |
dewey-hundreds | 600 - Technology (Applied sciences) |
dewey-ones | 610 - Medicine and health |
dewey-raw | 610 |
dewey-search | 610 |
dewey-sort | 3610 |
dewey-tens | 610 - Medicine and health |
discipline | Medizin |
doi_str_mv | 10.1007/b97639 |
edition | Fourth Edition |
format | Electronic eBook |
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spelling | Cassel, Christine K. Verfasser aut Geriatric Medicine An Evidence-Based Approach by Christine K. Cassel, Rosanne M. Leipzig, Harvey Jay Cohen, Eric B. Larson, Diane E. Meier, Carol F. Capello Fourth Edition New York, NY Springer New York 2003 1 Online-Ressource (L, 1318 p) txt rdacontent c rdamedia cr rdacarrier Since the publication of the third edition of Geriatric Medicine,extraordinary advances have occurred in the science of aging and the potential for biomedical research to give us answers to many, if not most, of the age-related disorders that threaten the quality of life in older years. At the most basic level, the successful mapping of the human genome was declared complete in the fall of 2000. Understanding the map of the human genome is as important as understanding the map of genomes of important laboratory species, ranging from the microscopic worms and fruit?ies used in most classic genetic studies to rodents such as laboratory mice, and eventually to primates, on which much of the research on the aging human brain is done. The genetic maps of all of these species,including our own,does not answer clinical questions,but it does open the door to dramatic, rapid, and ef?cient answers to questions about the genetic polymorphisms related to diseases in humans. The telomerase story also unfolded since the third edition. Telomerase is an enzyme responsible for maintaining the telomeres—the redundant DNA portions at the end of chromosomes—whose shortening seems to be linked directly to cell senescence,ap- tosis,and the control over cell death,which,at the level of the individual cell,seems to be linked to the decline of organ function and eventually aging and death within the org- ism General Practice / Family Medicine Geriatrics/Gerontology Family medicine Geriatrics Geriatrie (DE-588)4071745-8 gnd rswk-swf Alterskrankheit (DE-588)4132293-9 gnd rswk-swf Geriatrie (DE-588)4071745-8 s DE-604 Alterskrankheit (DE-588)4132293-9 s Leipzig, Rosanne M. aut Cohen, Harvey Jay aut Larson, Eric B. aut Erscheint auch als Druck-Ausgabe 9781475778373 Erscheint auch als Druck-Ausgabe 9780387955148 Erscheint auch als Druck-Ausgabe 9781475778366 https://doi.org/10.1007/b97639 Verlag URL des Erstveröffentlichers Volltext |
spellingShingle | Cassel, Christine K. Leipzig, Rosanne M. Cohen, Harvey Jay Larson, Eric B. Geriatric Medicine An Evidence-Based Approach General Practice / Family Medicine Geriatrics/Gerontology Family medicine Geriatrics Geriatrie (DE-588)4071745-8 gnd Alterskrankheit (DE-588)4132293-9 gnd |
subject_GND | (DE-588)4071745-8 (DE-588)4132293-9 |
title | Geriatric Medicine An Evidence-Based Approach |
title_auth | Geriatric Medicine An Evidence-Based Approach |
title_exact_search | Geriatric Medicine An Evidence-Based Approach |
title_full | Geriatric Medicine An Evidence-Based Approach by Christine K. Cassel, Rosanne M. Leipzig, Harvey Jay Cohen, Eric B. Larson, Diane E. Meier, Carol F. Capello |
title_fullStr | Geriatric Medicine An Evidence-Based Approach by Christine K. Cassel, Rosanne M. Leipzig, Harvey Jay Cohen, Eric B. Larson, Diane E. Meier, Carol F. Capello |
title_full_unstemmed | Geriatric Medicine An Evidence-Based Approach by Christine K. Cassel, Rosanne M. Leipzig, Harvey Jay Cohen, Eric B. Larson, Diane E. Meier, Carol F. Capello |
title_short | Geriatric Medicine |
title_sort | geriatric medicine an evidence based approach |
title_sub | An Evidence-Based Approach |
topic | General Practice / Family Medicine Geriatrics/Gerontology Family medicine Geriatrics Geriatrie (DE-588)4071745-8 gnd Alterskrankheit (DE-588)4132293-9 gnd |
topic_facet | General Practice / Family Medicine Geriatrics/Gerontology Family medicine Geriatrics Geriatrie Alterskrankheit |
url | https://doi.org/10.1007/b97639 |
work_keys_str_mv | AT casselchristinek geriatricmedicineanevidencebasedapproach AT leipzigrosannem geriatricmedicineanevidencebasedapproach AT cohenharveyjay geriatricmedicineanevidencebasedapproach AT larsonericb geriatricmedicineanevidencebasedapproach |