Cell death: apoptosis and other means to an end
Gespeichert in:
| Beteilige Person: | |
|---|---|
| Format: | Buch |
| Sprache: | Deutsch |
| Veröffentlicht: |
Cold Spring Harbor, New York
Cold Spring Harbor Laboratory Press
[2018]
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| Ausgabe: | Second edition |
| Schlagwörter: | |
| Links: | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=030625223&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=030625223&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |
| Umfang: | xix, 278 Seiten Illustrationen, Diagramme |
| ISBN: | 9781621822141 |
Internformat
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Datensatz im Suchindex
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| adam_text | Contents Foreword from the First Edition by Martin Raff, ix Preface from the First Edition, xi Foreword by Shigekazu Nagata, xiii Preface, xv Introduction, xvii 1 A Matter of Life and Death, 1 2 Caspases and Their Substrates, 11 3 Caspase Activation and Inhibition, 27 4 The Mitochondrial Pathway of Apoptosis, Part I: MOMPand Beyond, 45 5 The Mitochondrial Pathway of Apoptosis, Part II: the BCL-2 Protein Family, 61 6 The Death Receptor Pathway of Apoptosis, 89 7 Inflammasomes and Other Caspase-Activation Platforms, 103 8 Nonapoptotic Cell Death Pathways, 121 9 The Burial: Clearance and Consequences, 149 10 Cell Death in Development, 179 11 Cell Death and Cancer, 195 12 The Future of Death, 217 Figure Credits, 233 Additional Reading, 237 Index, 263 VII
CELL DEATH ss Apoptosis and Other Means to an End A million cells in our bodies die every second—they commit suicide by activating a process called apoptosis or other forms of programmed cell death. Illese mechanisms are essential for survival of the body as a whole and play critical roles in various developmental processes, the immune system, and cancer. In this second edition of Douglas Green’s essential book on cell death, Green retains the bottom-up approach of the first edition, starting with the enzymes that carry out the execution (caspases) and their cellular targets before examining the machinery that connects them to signals that cause cell death. He also describes the roles of cell death in development, neuronal selection, and the development of self-tolerance in the immune system, as well as how the body uses cell death to defend against cancer. The new edition is fully updated to cover the many recent advances in our understanding of the death machinery and signals that control cell death. These include the mechanisms regulating necroptosis, mitophagy, and newly identified processes, such as ferroptosis. The book will thus be of great interest to researchers actively working in the field, as well as biologists and undergraduates encountering the topic for the first time.
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| discipline | Biologie Medizin |
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| id | DE-604.BV045236955 |
| illustrated | Illustrated |
| indexdate | 2024-12-20T18:21:40Z |
| institution | BVB |
| isbn | 9781621822141 |
| language | German |
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| physical | xix, 278 Seiten Illustrationen, Diagramme |
| publishDate | 2018 |
| publishDateSearch | 2018 |
| publishDateSort | 2018 |
| publisher | Cold Spring Harbor Laboratory Press |
| record_format | marc |
| spellingShingle | Green, Douglas R. 1955- Cell death apoptosis and other means to an end Zelltod (DE-588)4207415-0 gnd Apoptosis (DE-588)4291096-1 gnd |
| subject_GND | (DE-588)4207415-0 (DE-588)4291096-1 |
| title | Cell death apoptosis and other means to an end |
| title_auth | Cell death apoptosis and other means to an end |
| title_exact_search | Cell death apoptosis and other means to an end |
| title_full | Cell death apoptosis and other means to an end Douglas R. Green (St. Jude Children's Research Hospital) |
| title_fullStr | Cell death apoptosis and other means to an end Douglas R. Green (St. Jude Children's Research Hospital) |
| title_full_unstemmed | Cell death apoptosis and other means to an end Douglas R. Green (St. Jude Children's Research Hospital) |
| title_short | Cell death |
| title_sort | cell death apoptosis and other means to an end |
| title_sub | apoptosis and other means to an end |
| topic | Zelltod (DE-588)4207415-0 gnd Apoptosis (DE-588)4291096-1 gnd |
| topic_facet | Zelltod Apoptosis |
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