Verfügbarkeit: Frankie starlight | Technische Universität München

Gespeichert in:

Bibliographische Detailangaben
Beteiligte Personen:	Raymo, Chet 1936- (VerfasserIn, DrehbuchautorIn), Bernstein, Elmer 1922-2004 (KomponistIn)
Weitere beteiligte Personen:	Laufer, Paul (Kameramann/frau), O'Leary, Ronan (DrehbuchautorIn), Byrne, Gabriel 1950- (SchauspielerIn), Parillaud, Anne 1960- (SchauspielerIn), Dillon, Matt 1964- (SchauspielerIn), Farrell, Colin 1976- (SchauspielerIn)
Format:	Video Software
Sprache:	Deutsch Englisch
Veröffentlicht:	[Habichtswald] ASTRO Distribution GmbH [2006]
Schlagwörter:	Film DVD-Video
Links:	http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=030501716&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
Beschreibung:	Original: Frankreich/Großbritannien/Irland/USA, 1995
Umfang:	1 DVD-Video (ca. 96 Min.) 12 cm
Zielpublikum:	FSK 12

Internformat

MARC


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Datensatz im Suchindex

_version_	1819300939743363072
adam_text	TABLE OF CONTENTS CHAPTER I - GENERAL INTRODUCTION 1 1.1 MICROJBIAL COMMUNITIES AND THE HUMAN MICROBIOME 1 1.2 CYSTIC FIBROSIS AND PATHOGENESIS 3 1.2.1 GENETIC BACKGROUND 4 1.2.2 PATHOGENESIS OF LUNG DISEASES 4 1.3 DIAGNOSTIC METHODS FOR RESPIRATORY INFECTIOUS DISEASES IN CLINIC AND RESEARCH 5 1.3.1 SSCP FINGERPRINTING 7 1.3.2 ILLUMINA-BASED NEXT GENERATION SEQUENCING 8 1.3.3 EXHALED BREATH ANALYSIS BASED ON VOC-BIOMARKER 9 1.4 STUDIES OF MICROBIAL INFECTIONS IN CF RESPIRATORY TRACTS 11 1.5 STUDIES OF EXHALED BREATH DIAGNOSTICS FOR LUNG DISEASES 14 1.6 STATISTICAL ANALYSIS 15 1.7 RESEARCH APPROACH 16 1.7.1 OBJECTIVES OF THESIS 17 1.8 REFERENCES 18 CHAPTER II - ASSESSMENT OF DISTINCT BACTERIAL COMMUNITIES AND THEIR PATHOGENIC POTENTIAL IN SPUTUM FROM ADULT CYSTIC FIBROSIS PATIENTS 27 2.1 ABSTRACT 28 2.2 INTRODUCTION 29 2.3 MATERIAL AND METHODS 30 2.3.1 PATIENT COHORT AND SAMPLE COLLECTION 30 2.3.2 SPUTUM PREPARATION AND DNA EXTRACTION 31 2.3.3 FINGERPRINTS BY SSCP ELECTROPHORESIS AND SEQUENCING OF INDIVIDUAL BANDS 31 2.3.4 PREPARATION OF ILLUMINA HIGH-THROUGHPUT SEQUENCING 32 2.3.5 DATA PROCESSING AND PHYLOGENETIC ANALYSIS 33 2.3.6 STATISTICAL ANALYSIS 34 IX HTTP://D-NB.INFO/1048214869 2.4 RESULTS 34 2.4.1 COMPARISONS OF METHODS FOR MICROBIAL COMPOSITION PROFILING 34 2.4.2 COMMUNITY COMPOSITION AND DOMINANT BACTERIAL SPECIES 41 2.4.3 COMPARISON OF HOST FACTORS AND THE BACTERIAL COMMUNITY COMPOSITION 43 2.4.4 COMMUNITY COMPOSITION AND POLYMICROBIAL CONSORTIA 45 2.4.5 COMMUNITY DYNAMICS 49 2.5 DISCUSSION 51 2.5.1 VALIDATION OF METHODS FOR MICROBIAL COMMUNITY PROFILING 51 2.5.2 SINGLE BACTERIAL SPECIES VERSUS POLYMICROBIAL CONSORTIA 52 2.5.3 CLINICAL RELEVANCE OF BACTERIAL SPECIES IS DEPENDING ON CONSORTIA 54 2.6 REFERENCES 56 2.7 SUPPLEMENTARY MATERIAL 60 CHAPTER III - CHARACTERIZATION OF FUNGAL AND BACTERIAL COMMUNITIES IN SPUTUM SAMPLES FROM ADULT PATIENTS WITH CYSTIC FIBROSIS 68 3.1 ABSTRACT 69 3.2 INTRODUCTION 70 3.3 MATERIAL AND METHODS 72 3.3.1 SAMPLE COLLECTION 72 3.3.2 SPUTUM PREPARATION AND DNA EXTRACTION 72 3.3.3 PCR AMPLIFICATION AND PREPARATION OF SSDNA 73 3.3.4 SSCP FINGERPRINTS AND SEQUENCING OF INDIVIDUAL SSDNA BANDS 73 3.3.5 DATA PROCESSING AND PHYLOGENETIC ANALYSIS 74 3.4 RESULTS 75 3.4.1 COMPARISON OF FUNGAL AND BACTERIAL SPECIES RICHNESS IN CF COHORT 75 3.4.2 SPECIES DIVERSITY AND OCCURRENCE FREQUENCY OF BACTERIA IN CF COHORT 78 3.4.3 SPECIES DIVERSITY AND OCCURRENCE FREQUENCY OF FUNGI IN CF COHORT 80 3.4.4 DYNAMICS OF FUNGAL OTUS AND CLINICAL ABNORMALITIES IN INDIVIDUAL CF PATIENTS ... 82 3.5 DISCUSSION 85 3.5.1 MICROBIAL SPECIES IDENTIFICATION 85 3.5.2 BACTERIAL SPECIES PRESENT IN CF SPUTUM 86 X 3.5.3 FUNGAL SPECIES PRESENT IN CF SPUTUM 88 3.5.4 CLINICAL RELEVANCE OF FUNGAL SPECIES 90 3.6 CONCLUSION & OUTLOOK 91 3.7 REFERENCES 92 3.8 SUPPLEMENTARY MATERIAL 97 CHAPTER IV - MONITORING THE VOCS COMPOSITION OF MAJOR MICROBIAL PATHOGENS FOR CLINICAL DIAGNOSTIC PURPOSES 103 4.1 ABSTRACT 104 4.2 INTRODUCTION 105 4.3 MATERIAL AND METHODS 107 4.3.1 CELL CULTURE AND MICROBIAL STRAIN PREPARATION 107 4.3.2 MICROBIAL IN VITRO MODELS FOR MEASUREMENTS OF VOC EMISSIONS 107 4.3.3 IMAGING OF HOST-PATHOGEN INTERACTION CULTURES 108 4.3.4 SOLID PHASE MICRO-EXTRACTION (SPME) 109 4.3.5 GAS CHROMATOGRAPHY/MASS SPECTROSCOPY (GC/MS) PARAMETERS 109 4.3.6 CF COHORT 110 4.3.7 IN VIVO BREATH SAMPLING 110 4.3.8 DATA PROCESSING AND STATISTICAL ANALYSIS 110 4.4 RESULTS 112 4.4.1 IN VITRO VOCS MONITORING IN BIOFILMS OF CF PATHOGENS 112 4.4.2 IN VITRO VOCS MONITORING IN HOST-PATHOGEN INTERACTION CULTURES (A549 CELLS) 115 4.4.3 IN VIVO VOCS MONITORING IN EXHALED BREATH OF CF PATIENTS 121 4.5 DISCUSSION 124 4.5.1 RELEVANCE OF APPROPRIATE STATISTICAL METHODS IN VOC EMISSION ANALYSIS 124 4.5.2 APPLICATION OF IN VITRO VOC EMISSION MODELS FOR MICROBIAL DISCRIMINATION 124 4.5.3 FEASIBILITY OF EXHALED VOCS ANALYSIS FOR DIAGNOSTICS OF PULMONARY INFECTIONS... 126 4.6 CONCLUSION AND PERSPECTIVES 128 4.7 REFERENCES 128 4.8 SUPPLEMENTARY MATERIAL 133 XI CHAPTER V - GENERAL DISCUSSION 134 5.1 DIAGNOSTIC METHODS FOR LOWER RESPIRATORY INFECTIONS 134 5.2 MICROBIAL COMMUNITY STRUCTURE AND COMPOSITION IN CF SPUTUM 135 5.3 IMPACT OF COMMUNITIES ON MICROBIAL INFECTIONS 137 5.4 OUTLOOK AND CONCLUSION 139 5.5 REFERENCES 140 APPENDIX 143 XII
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author	Raymo, Chet 1936- Bernstein, Elmer 1922-2004
author2	Laufer, Paul Raymo, Chet 1936- O'Leary, Ronan Byrne, Gabriel 1950- Parillaud, Anne 1960- Dillon, Matt 1964- Farrell, Colin 1976-
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author_facet	Raymo, Chet 1936- Bernstein, Elmer 1922-2004 Laufer, Paul Raymo, Chet 1936- O'Leary, Ronan Byrne, Gabriel 1950- Parillaud, Anne 1960- Dillon, Matt 1964- Farrell, Colin 1976-
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genre	(DE-588)4017102-4 Film gnd-content (DE-588)4585125-6 DVD-Video gnd-carrier
genre_facet	Film DVD-Video
id	DE-604.BV045111402
illustrated	Not Illustrated
indexdate	2024-12-20T18:18:20Z
institution	BVB
language	German English
oai_aleph_id	oai:aleph.bib-bvb.de:BVB01-030501716
oclc_num	1048214869
open_access_boolean
owner	DE-384
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physical	1 DVD-Video (ca. 96 Min.) 12 cm
publishDate	2006
publishDateSearch	2005
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publisher	ASTRO Distribution GmbH
record_format	marc
spellingShingle	Raymo, Chet 1936- Bernstein, Elmer 1922-2004 Frankie starlight
subject_GND	(DE-588)4017102-4 (DE-588)4585125-6
title	Frankie starlight
title_auth	Frankie starlight
title_exact_search	Frankie starlight
title_full	Frankie starlight Regie: Michael Lindsay-Hogg ; Kamera: Paul Laufer ; Drehbuch: Chet Raymo und Ronan O'Leary ; mit Matt Dillon, Anne Parillaud, Gabriel Byrne ; Musik: Elmer Bernstein ; nach dem Roman von Chet Raymo
title_fullStr	Frankie starlight Regie: Michael Lindsay-Hogg ; Kamera: Paul Laufer ; Drehbuch: Chet Raymo und Ronan O'Leary ; mit Matt Dillon, Anne Parillaud, Gabriel Byrne ; Musik: Elmer Bernstein ; nach dem Roman von Chet Raymo
title_full_unstemmed	Frankie starlight Regie: Michael Lindsay-Hogg ; Kamera: Paul Laufer ; Drehbuch: Chet Raymo und Ronan O'Leary ; mit Matt Dillon, Anne Parillaud, Gabriel Byrne ; Musik: Elmer Bernstein ; nach dem Roman von Chet Raymo
title_short	Frankie starlight
title_sort	frankie starlight
topic_facet	Film DVD-Video
url	http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=030501716&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
work_keys_str_mv	AT lindsayhoggmichael frankiestarlight AT lauferpaul frankiestarlight AT raymochet frankiestarlight AT olearyronan frankiestarlight AT byrnegabriel frankiestarlight AT parillaudanne frankiestarlight AT dillonmatt frankiestarlight AT farrellcolin frankiestarlight AT bernsteinelmer frankiestarlight

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