Saved in:
| Main Author: | |
|---|---|
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Cambridge
Cambridge University Press
2009
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| Subjects: | |
| Links: | https://doi.org/10.1017/CBO9780511575853 https://doi.org/10.1017/CBO9780511575853 https://doi.org/10.1017/CBO9780511575853 |
| Summary: | Since its discovery 50 years ago, brain dopamine has been implicated in the control of movement and cognition, and is concerned with diverse brain diseases such as Parkinson's disease, schizophrenia and drug addiction. This book is an illustrated biography of the dopamine molecule, from its synthesis in the brain to its signalling mechanisms and ultimately to its metabolic breakdown. Using colour illustrations of positron emission tomography (PET) scans, each chapter presents a specific stage in the biochemical pathway for dopamine. Writing for researchers and graduate students, Paul Cumming presents a compilation of all that has been learned about dopamine through molecular imaging, a technology which allows the measurement of formerly invisible processes in the living brain. He reviews current technical controversies in the interpretation of dopamine imaging, and presents key results illuminating brain dopamine in illness and health |
| Item Description: | Title from publisher's bibliographic system (viewed on 05 Oct 2015) |
| Physical Description: | 1 online resource (xv, 340 pages) |
| ISBN: | 9780511575853 |
| DOI: | 10.1017/CBO9780511575853 |
Staff View
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| 500 | |a Title from publisher's bibliographic system (viewed on 05 Oct 2015) | ||
| 505 | 8 | |a The life history of dopamine -- Enzymology of tyrosine hydroxylase -- The assay of tyrosine hydroxylase -- Enzymology of aromatic amino acid decarboxylase -- PET studies of DOPA utilization -- Conjugation and sulfonation of dopamine and its metabolites -- Dopamine synthesis and metabolism rates -- MAO activity in the brain -- Vesicular storage of dopamine -- Dopamine release : from vesicles to behavior -- The plasma membrane dopamine transporter -- Dopamine receptors -- Imaging dopamine D1 receptors -- Imaging dopamine D2 receptors -- Factors influencing D2 binding in living brain -- The absolute abundance of dopamine receptors in brain | |
| 520 | |a Since its discovery 50 years ago, brain dopamine has been implicated in the control of movement and cognition, and is concerned with diverse brain diseases such as Parkinson's disease, schizophrenia and drug addiction. This book is an illustrated biography of the dopamine molecule, from its synthesis in the brain to its signalling mechanisms and ultimately to its metabolic breakdown. Using colour illustrations of positron emission tomography (PET) scans, each chapter presents a specific stage in the biochemical pathway for dopamine. Writing for researchers and graduate students, Paul Cumming presents a compilation of all that has been learned about dopamine through molecular imaging, a technology which allows the measurement of formerly invisible processes in the living brain. He reviews current technical controversies in the interpretation of dopamine imaging, and presents key results illuminating brain dopamine in illness and health | ||
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| contents | The life history of dopamine -- Enzymology of tyrosine hydroxylase -- The assay of tyrosine hydroxylase -- Enzymology of aromatic amino acid decarboxylase -- PET studies of DOPA utilization -- Conjugation and sulfonation of dopamine and its metabolites -- Dopamine synthesis and metabolism rates -- MAO activity in the brain -- Vesicular storage of dopamine -- Dopamine release : from vesicles to behavior -- The plasma membrane dopamine transporter -- Dopamine receptors -- Imaging dopamine D1 receptors -- Imaging dopamine D2 receptors -- Factors influencing D2 binding in living brain -- The absolute abundance of dopamine receptors in brain |
| ctrlnum | (ZDB-20-CBO)CR9780511575853 (OCoLC)967604273 (DE-599)BVBBV043945414 |
| dewey-full | 612.8/042 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 612 - Human physiology |
| dewey-raw | 612.8/042 |
| dewey-search | 612.8/042 |
| dewey-sort | 3612.8 242 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| doi_str_mv | 10.1017/CBO9780511575853 |
| format | Electronic eBook |
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| genre | 1\p (DE-588)4113937-9 Hochschulschrift gnd-content |
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| id | DE-604.BV043945414 |
| illustrated | Not Illustrated |
| indexdate | 2024-12-20T17:49:25Z |
| institution | BVB |
| isbn | 9780511575853 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-029354385 |
| oclc_num | 967604273 |
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| owner_facet | DE-12 DE-92 |
| physical | 1 online resource (xv, 340 pages) |
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| publishDate | 2009 |
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| publisher | Cambridge University Press |
| record_format | marc |
| spelling | Cumming, Paul Verfasser aut Imaging dopamine Paul Cumming Cambridge Cambridge University Press 2009 1 online resource (xv, 340 pages) txt rdacontent c rdamedia cr rdacarrier Title from publisher's bibliographic system (viewed on 05 Oct 2015) The life history of dopamine -- Enzymology of tyrosine hydroxylase -- The assay of tyrosine hydroxylase -- Enzymology of aromatic amino acid decarboxylase -- PET studies of DOPA utilization -- Conjugation and sulfonation of dopamine and its metabolites -- Dopamine synthesis and metabolism rates -- MAO activity in the brain -- Vesicular storage of dopamine -- Dopamine release : from vesicles to behavior -- The plasma membrane dopamine transporter -- Dopamine receptors -- Imaging dopamine D1 receptors -- Imaging dopamine D2 receptors -- Factors influencing D2 binding in living brain -- The absolute abundance of dopamine receptors in brain Since its discovery 50 years ago, brain dopamine has been implicated in the control of movement and cognition, and is concerned with diverse brain diseases such as Parkinson's disease, schizophrenia and drug addiction. This book is an illustrated biography of the dopamine molecule, from its synthesis in the brain to its signalling mechanisms and ultimately to its metabolic breakdown. Using colour illustrations of positron emission tomography (PET) scans, each chapter presents a specific stage in the biochemical pathway for dopamine. Writing for researchers and graduate students, Paul Cumming presents a compilation of all that has been learned about dopamine through molecular imaging, a technology which allows the measurement of formerly invisible processes in the living brain. He reviews current technical controversies in the interpretation of dopamine imaging, and presents key results illuminating brain dopamine in illness and health Dopamine Tomography, Emission Single-photon emission computed tomography Molecular radiobiology 1\p (DE-588)4113937-9 Hochschulschrift gnd-content Erscheint auch als Druckausgabe 978-0-521-79002-4 https://doi.org/10.1017/CBO9780511575853 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Cumming, Paul Imaging dopamine The life history of dopamine -- Enzymology of tyrosine hydroxylase -- The assay of tyrosine hydroxylase -- Enzymology of aromatic amino acid decarboxylase -- PET studies of DOPA utilization -- Conjugation and sulfonation of dopamine and its metabolites -- Dopamine synthesis and metabolism rates -- MAO activity in the brain -- Vesicular storage of dopamine -- Dopamine release : from vesicles to behavior -- The plasma membrane dopamine transporter -- Dopamine receptors -- Imaging dopamine D1 receptors -- Imaging dopamine D2 receptors -- Factors influencing D2 binding in living brain -- The absolute abundance of dopamine receptors in brain Dopamine Tomography, Emission Single-photon emission computed tomography Molecular radiobiology |
| subject_GND | (DE-588)4113937-9 |
| title | Imaging dopamine |
| title_auth | Imaging dopamine |
| title_exact_search | Imaging dopamine |
| title_full | Imaging dopamine Paul Cumming |
| title_fullStr | Imaging dopamine Paul Cumming |
| title_full_unstemmed | Imaging dopamine Paul Cumming |
| title_short | Imaging dopamine |
| title_sort | imaging dopamine |
| topic | Dopamine Tomography, Emission Single-photon emission computed tomography Molecular radiobiology |
| topic_facet | Dopamine Tomography, Emission Single-photon emission computed tomography Molecular radiobiology Hochschulschrift |
| url | https://doi.org/10.1017/CBO9780511575853 |
| work_keys_str_mv | AT cummingpaul imagingdopamine |
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