Gespeichert in:
Bibliographische Detailangaben
Weitere beteiligte Personen: Do, Kim-Anh 1960- (HerausgeberIn), Müller, Peter 1963 August 9- (HerausgeberIn), Vannucci, Marina 1966- (HerausgeberIn)
Format: Elektronisch E-Book
Sprache:Englisch
Veröffentlicht: Cambridge Cambridge University Press 2006
Schlagwörter:
Links:https://doi.org/10.1017/CBO9780511584589
https://doi.org/10.1017/CBO9780511584589
https://doi.org/10.1017/CBO9780511584589
Zusammenfassung:The interdisciplinary nature of bioinformatics presents a research challenge in integrating concepts, methods, software and multiplatform data. Although there have been rapid developments in new technology and an inundation of statistical methods for addressing other types of high-throughput data, such as proteomic profiles that arise from mass spectrometry experiments. This book discusses the development and application of Bayesian methods in the analysis of high-throughput bioinformatics data that arise from medical, in particular, cancer research, as well as molecular and structural biology. The Bayesian approach has the advantage that evidence can be easily and flexibly incorporated into statistical methods. A basic overview of the biological and technical principles behind multi-platform high-throughput experimentation is followed by expert reviews of Bayesian methodology, tools and software for single group inference, group comparisons, classification and clustering, motif discovery and regulatory networks, and Bayesian networks and gene interactions
Beschreibung:Title from publisher's bibliographic system (viewed on 05 Oct 2015)
Umfang:1 online resource (xviii, 437 pages)
ISBN:9780511584589
DOI:10.1017/CBO9780511584589

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