Verfügbarkeit: Data mining for important amino acid residues in multiple sequence alignments and protein structures

Data mining for important amino acid residues in multiple sequence alignments and protein structures:

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Bibliographische Detailangaben
Beteilige Person:	Janda, Jan-Oliver (VerfasserIn)
Format:	Hochschulschrift/Dissertation Buch
Sprache:	Englisch
Veröffentlicht:	2014
Schlagwörter:	Aminosäuren Enzym Strukturaufklärung Molekulare Bioinformatik Hochschulschrift
Links:	http://epub.uni-regensburg.de/29907/ https://nbn-resolving.org/urn:nbn:de:bvb:355-epub-299076 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027292326&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
Umfang:	VIII, 129 S. Ill., graph. Darst.

Internformat

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Datensatz im Suchindex

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adam_text	DATA MINING FOR IMPORTANT AMINO ACID RESIDUES IN MULTIPLE SEQUENCE ALIGNMENTS AND PROTEIN STRUCTURES DISSERTATION ZUR ERLANGUNG DES DOKTORGRADES DER NATURWISSENSCHAFTEN (DR. RER. NAT.) DER FAKULTAT FUR BIOLOGIE UND VORKLINISCHE MEDIZIN DER UNIVERSITAT REGENSBURG VORGELEGT VON JAN-OLIVER JANDA AUS LINZ, OSTERREICH IM JAHR 2014 HTTP://D-NB.INFO/1052155294 CONTENTS LIST OF FIGURES III LIST OF TABLES V ABBREVIATIONS VII ABSTRACT 1 ZUSAMMENFASSUNG 3 1 INTRODUCTION 5 1.1 PROTEINS AND ENZYMES 5 1.2 MACHINE LEARNING 9 1.3 PROTEIN STRUCTURES 12 1.4 MULTIPLE SEQUENCE ALIGNMENTS 14 1.5 AIM OF THIS WORK 19 2 SUMMARY AND DISCUSSION 21 2.1 CLASSIFICATION OF HIGHLY CONSERVED RESIDUE POSITIONS 21 2.1.1 CLIPS-ID: A SOLELY SEQUENCE-BASED CLASSIFIER 22 2.1.2 CLIPS-3D: A SOLELY STRUCTURE-BASED CLASSIFIER 28 2.1.3 CLIPS-4D: A SEQUENCE- AND STRUCTURE-BASED CLASSIFIER ... 29 2.2 IDENTIFICATION OF CORRELATED MUTATIONS 34 CONTENTS 2.2.1 STATISTICAL ANALYSIS 35 2.2.2 CASE STUDIES THAT ILLUSTRATE CLASSIFICATION PERFORMANCE ... 37 3 BIBLIOGRAPHY 43 4 LIST OF PUBLICATIONS AND PERSONAL CONTRIBUTION 67 5 PUBLICATIONS 69 5.1 PUBLICATION A 69 5.2 PUBLICATION B 81 5.3 PUBLICATION C 115 6 ACKNOWLEDGEMENT 129 II
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spellingShingle	Janda, Jan-Oliver Data mining for important amino acid residues in multiple sequence alignments and protein structures Aminosäuren (DE-588)4142205-3 gnd Enzym (DE-588)4014988-2 gnd Strukturaufklärung (DE-588)4183788-5 gnd Molekulare Bioinformatik (DE-588)4531334-9 gnd
subject_GND	(DE-588)4142205-3 (DE-588)4014988-2 (DE-588)4183788-5 (DE-588)4531334-9 (DE-588)4113937-9
title	Data mining for important amino acid residues in multiple sequence alignments and protein structures
title_auth	Data mining for important amino acid residues in multiple sequence alignments and protein structures
title_exact_search	Data mining for important amino acid residues in multiple sequence alignments and protein structures
title_full	Data mining for important amino acid residues in multiple sequence alignments and protein structures von Jan-Oliver Janda
title_fullStr	Data mining for important amino acid residues in multiple sequence alignments and protein structures von Jan-Oliver Janda
title_full_unstemmed	Data mining for important amino acid residues in multiple sequence alignments and protein structures von Jan-Oliver Janda
title_short	Data mining for important amino acid residues in multiple sequence alignments and protein structures
title_sort	data mining for important amino acid residues in multiple sequence alignments and protein structures
topic	Aminosäuren (DE-588)4142205-3 gnd Enzym (DE-588)4014988-2 gnd Strukturaufklärung (DE-588)4183788-5 gnd Molekulare Bioinformatik (DE-588)4531334-9 gnd
topic_facet	Aminosäuren Enzym Strukturaufklärung Molekulare Bioinformatik Hochschulschrift
url	http://epub.uni-regensburg.de/29907/ https://nbn-resolving.org/urn:nbn:de:bvb:355-epub-299076 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027292326&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
work_keys_str_mv	AT jandajanoliver dataminingforimportantaminoacidresiduesinmultiplesequencealignmentsandproteinstructures

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