Structural and Functional Characterization of the Immunoproteasome:
Gespeichert in:
| Beteilige Person: | |
|---|---|
| Format: | Hochschulschrift/Dissertation Elektronisch E-Book |
| Sprache: | Englisch |
| Veröffentlicht: |
Cham [u.a.]
Springer International Publishing Switzerland
2013
|
| Schriftenreihe: | Springer Theses
|
| Schlagwörter: | |
| Links: | https://doi.org/10.1007/978-3-319-01556-9 https://doi.org/10.1007/978-3-319-01556-9 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=026826663&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=026826663&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |
| Umfang: | 1 Online-Ressource |
| ISBN: | 9783319015569 |
| DOI: | 10.1007/978-3-319-01556-9 |
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Datensatz im Suchindex
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|---|---|
| adam_text | STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF THE IMMUNOPROTEASOME
/ HUBER, EVA MARIA
: 2013
TABLE OF CONTENTS / INHALTSVERZEICHNIS
INTRODUCTION
OBJECTIVE
MATERIALS AND METHODS
RESULTS
DISCUSSION
APPENDIX
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF THE IMMUNOPROTEASOME
/ HUBER, EVA MARIA
: 2013
ABSTRACT / INHALTSTEXT
IN THIS ACCLAIMED THESIS, EVA MARIA HUBER REVEALS GROUND-BREAKING
RESULTS BY ELUCIDATING THE CRYSTAL STRUCTURE OF THE MURINE
IMMUNOPROTEASOME IN COMPLEX WITH A SELECTIVE INHIBITOR. HUBER DOES THIS
BY PERFORMING MULTIDISCIPLINARY METHODOLOGIES INCLUDING X-RAY
CRYSTALLOGRAPHY, FLUORESCENCE SPECTROSCOPY AND MUTAGENESIS EXPERIMENTS.
HER EXCEPTIONAL RESULTS EXPLORE THE IMMUNOPROTEASOME COMPLEX STRUCTURES
AND ARE OF OUTSTANDING IMPORTANCE FOR FUTURE SCIENTIFIC RESEARCH
ESPECIALLY IN THE PHARMACEUTICAL INDUSTRY. THESE RESULTS WILL ENABLE THE
FUNCTIONAL ANALYSIS OF INDIVIDUAL PROTEASOME SUBUNITS AND SUPPORT THE
DEVELOPMENT OF NOVEL DRUGS FOR AUTOIMMUNE DISEASES SUCH AS MULTIPLE
SCLEROSIS OR RHEUMATOID ARTHRITIS
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
|
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| dewey-ones | 543 - Analytical chemistry |
| dewey-raw | 543 |
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| discipline | Chemie / Pharmazie |
| doi_str_mv | 10.1007/978-3-319-01556-9 |
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| spellingShingle | Huber, Eva Maria Structural and Functional Characterization of the Immunoproteasome Proteasen (DE-588)4047521-9 gnd Autoimmunität (DE-588)4319435-7 gnd |
| subject_GND | (DE-588)4047521-9 (DE-588)4319435-7 (DE-588)4113937-9 |
| title | Structural and Functional Characterization of the Immunoproteasome |
| title_auth | Structural and Functional Characterization of the Immunoproteasome |
| title_exact_search | Structural and Functional Characterization of the Immunoproteasome |
| title_full | Structural and Functional Characterization of the Immunoproteasome Eva Maria Huber |
| title_fullStr | Structural and Functional Characterization of the Immunoproteasome Eva Maria Huber |
| title_full_unstemmed | Structural and Functional Characterization of the Immunoproteasome Eva Maria Huber |
| title_short | Structural and Functional Characterization of the Immunoproteasome |
| title_sort | structural and functional characterization of the immunoproteasome |
| topic | Proteasen (DE-588)4047521-9 gnd Autoimmunität (DE-588)4319435-7 gnd |
| topic_facet | Proteasen Autoimmunität Hochschulschrift |
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