Interleukin-2 Receptor Expression in Canine Cutaneous Mast Cell Tumors:
Gespeichert in:
| Beteilige Person: | |
|---|---|
| Format: | Hochschulschrift/Dissertation Buch |
| Sprache: | Englisch |
| Veröffentlicht: |
Berlin
Mensch-und-Buch-Verl.
2013
|
| Schlagwörter: | |
| Links: | http://www.diss.fu-berlin.de/diss/receive/FUDISS_thesis_000000094584 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=026113509&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| Beschreibung: | Nebentitel: Interleukin-2-Rezeptor Expression in kaninen kutanen Mastzelltumoren |
| Umfang: | X, 64 S. Ill., graph. Darst. |
| ISBN: | 9783863873172 |
Internformat
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| 245 | 1 | 0 | |a Interleukin-2 Receptor Expression in Canine Cutaneous Mast Cell Tumors |c submitted by Anja Marina Meyer |
| 246 | 1 | 3 | |a Interleukin-2-Rezeptor Expression in kaninen kutanen Mastzelltumoren |
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| 650 | 7 | |a immunohistochemistry |2 cabt | |
| 650 | 7 | |a interleukin 2 |2 cabt | |
| 650 | 7 | |a mast cells |2 cabt | |
| 650 | 7 | |a neoplasms |2 cabt | |
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Datensatz im Suchindex
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| adam_text | IMAGE 1
CONTENTS
LIST OF ABBREVIATIONS IX
LIST OF TABLES X
LIST OF FIGURES X
LIST OF SUPPLEMENTAL MATERIAL X
1 INTRODUCTION 1
1.1 CANINE MAST CELL TUMORS (MCT) 1
1.1.1 DIAGNOSTIC APPROACH TO MCT 1
1.1.2 GRADING SYSTEMS AND THEIR PROGNOSTIC SIGNIFICANCE 2
1.1.2.1 PATNAIK GRADING SYSTEM 3
1.1.2.2 KIUPEL GRADING SYSTEM 4
1.1.2.3 CLINICAL STAGING 4
1.1.2.4 PROGNOSTIC SIGNIFICANCE 4
1.1.3 ADDITIONAL PROGNOSTIC FACTORS 5
1.1.3.1 BREED 5
1.1.3.2 LOCATION AND TUMOR SIZE 6
1.1.3.3 PROLIFERATION MARKERS 6
1.1.3.4 KIT RECEPTOR AND C-K7TMUTATION 7
1.1.4 MOLECULAR CARCINOGENESIS 7
1.2 THE LNTERLEUKIN-2 RECEPTOR (IL-2R) AND HUMAN MASTOCYTOSIS 8
1.2.1 CLASSIFICATION OF HUMAN MASTOCYTOSIS 8
1.2.2 CD25 IN HUMAN MASTOCYTOSIS 8
1.2.3 STRUCTURE AND FUNCTION OF THE IL-2R 9
1.2.4 IL-2R SUBUNITS AND THE LIGAND LNTERLEUKIN-2 (IL-2) 10
1.2.5 ROLE OF IL-2R IN TUMORS 11
1.3 AIMS AND HYPOTHESES 11
2 RESEARCH PUBLICATIONS IN JOURNALS WITH PEER-REVIEW 13
2.1 CD25 IS EXPRESSED BY CANINE CUTANEOUS MAST CELL TUMORS BUT NOT BY
CUTANEOUS CONNECTIVE TISSUE MAST CELLS 13
HTTP://D-NB.INFO/1036562166
IMAGE 2
CONTENTS
2.2 ALL SUBUNITS OF THE LNTERLEUKIN-2 RECEPTOR ARE EXPRESSED BY CANINE
CUTANEOUS
MAST CELL TUMOURS 24
3 DECLARATION OF OWN PORTIONS OF WORK IN THE RESEARCH PUBLICATIONS 36
3.1 CD25 IS EXPRESSED BY CANINE CUTANEOUS MAST CELL TUMORS BUT NOT BY
CUTANEOUS CONNECTIVE TISSUE MAST CELLS 36
3.2 ALL SUBUNITS OF THE LNTERLEUKIN-2 RECEPTOR ARE EXPRESSED BY CANINE
CUTANEOUS
MAST CELL TUMOURS 36
4 CONCLUDING DISCUSSION 37
4.1 FIRST HYPOTHESIS 37
4.2 SECOND HYPOTHESIS 39
4.3 THERAPEUTIC RELEVANCE OF IL-2R EXPRESSION IN CANINE MCT 41
4.4 CONCLUSION 42
4.5 OUTLOOK 42
5 SUMMARY 44
6 ZUSAMMENFASSUNG 46
7 REFERENCES 48
8 SUPPLEMENTAL MATERIAL 61
9 PUBLICATIONS 62
10 ACKNOWLEDGMENTS / DANKSAGUNG 63
SELBSTANDIGKEITSERKLARUNG 64
|
| any_adam_object | 1 |
| author | Meyer, Anja Marina |
| author_facet | Meyer, Anja Marina |
| author_role | aut |
| author_sort | Meyer, Anja Marina |
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| dewey-full | 630 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 630 - Agriculture and related technologies |
| dewey-raw | 630 |
| dewey-search | 630 |
| dewey-sort | 3630 |
| dewey-tens | 630 - Agriculture and related technologies |
| discipline | Agrar-/Forst-/Ernährungs-/Haushaltswissenschaft / Gartenbau |
| format | Thesis Book |
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| genre_facet | Hochschulschrift |
| id | DE-604.BV041137806 |
| illustrated | Illustrated |
| indexdate | 2024-12-20T16:31:36Z |
| institution | BVB |
| isbn | 9783863873172 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-026113509 |
| oclc_num | 862962412 |
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| physical | X, 64 S. Ill., graph. Darst. |
| psigel | ebook |
| publishDate | 2013 |
| publishDateSearch | 2013 |
| publishDateSort | 2013 |
| publisher | Mensch-und-Buch-Verl. |
| record_format | marc |
| spellingShingle | Meyer, Anja Marina Interleukin-2 Receptor Expression in Canine Cutaneous Mast Cell Tumors dogs cabt immunohistochemistry cabt interleukin 2 cabt mast cells cabt neoplasms cabt real time PCR cabt receptors cabt Interleukin 2 (DE-588)4162018-5 gnd Mastozytom (DE-588)7665483-7 gnd Hund (DE-588)4026181-5 gnd Rezeptor (DE-588)4049722-7 gnd |
| subject_GND | (DE-588)4162018-5 (DE-588)7665483-7 (DE-588)4026181-5 (DE-588)4049722-7 (DE-588)4113937-9 |
| title | Interleukin-2 Receptor Expression in Canine Cutaneous Mast Cell Tumors |
| title_alt | Interleukin-2-Rezeptor Expression in kaninen kutanen Mastzelltumoren |
| title_auth | Interleukin-2 Receptor Expression in Canine Cutaneous Mast Cell Tumors |
| title_exact_search | Interleukin-2 Receptor Expression in Canine Cutaneous Mast Cell Tumors |
| title_full | Interleukin-2 Receptor Expression in Canine Cutaneous Mast Cell Tumors submitted by Anja Marina Meyer |
| title_fullStr | Interleukin-2 Receptor Expression in Canine Cutaneous Mast Cell Tumors submitted by Anja Marina Meyer |
| title_full_unstemmed | Interleukin-2 Receptor Expression in Canine Cutaneous Mast Cell Tumors submitted by Anja Marina Meyer |
| title_short | Interleukin-2 Receptor Expression in Canine Cutaneous Mast Cell Tumors |
| title_sort | interleukin 2 receptor expression in canine cutaneous mast cell tumors |
| topic | dogs cabt immunohistochemistry cabt interleukin 2 cabt mast cells cabt neoplasms cabt real time PCR cabt receptors cabt Interleukin 2 (DE-588)4162018-5 gnd Mastozytom (DE-588)7665483-7 gnd Hund (DE-588)4026181-5 gnd Rezeptor (DE-588)4049722-7 gnd |
| topic_facet | dogs immunohistochemistry interleukin 2 mast cells neoplasms real time PCR receptors Interleukin 2 Mastozytom Hund Rezeptor Hochschulschrift |
| url | http://www.diss.fu-berlin.de/diss/receive/FUDISS_thesis_000000094584 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=026113509&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT meyeranjamarina interleukin2receptorexpressionincaninecutaneousmastcelltumors AT meyeranjamarina interleukin2rezeptorexpressioninkaninenkutanenmastzelltumoren |