Biological therapeutics:
Gespeichert in:
| Beteiligte Personen: | , |
|---|---|
| Format: | Buch |
| Sprache: | Englisch |
| Veröffentlicht: |
London [u.a.]
Pharmaceutical Press
2011
|
| Ausgabe: | 1. publ. |
| Schlagwörter: | |
| Links: | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=024787520&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| Umfang: | XII, 138 S. Ill., graph. Darst. |
| ISBN: | 9780853698432 0853698430 9783769254624 |
Internformat
MARC
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Datensatz im Suchindex
| _version_ | 1819274774908502016 |
|---|---|
| adam_text | Contents
Preface
xi
About the authors
xiii
1
Introduction to genetic manipulation
1
Nucleotides and the genetic code
3
Recombinam
DNA
technology
4
The tools used for
recombinant
DNA
technology
5
Mass production of insulin: an example
9
Knockout mice
Ю
Multiple choice questions
11
Further reading
12
2
Vaccines
13
Définition
of a vaccine
13
A brief history
13
Miniglossary
14
Immunity
15
Mechanism of action of vaccines
17
Production of vaccines
17
Modern production methods
17
Paradigm of a coordinated response to the threat
of an influenza pandemic
19
Some examples of specific vaccines
20
Multiple choice questions
25
References
27
Further reading
27
3
Hormone-related drugs
29
Brief history
30
Thyroid hormones
31
Adrenal hormones
35
The sex hormones
40
viii
I Contents
Biological drugs and cancer chemotherapy 41
Calcitonin 42
Parathyroid hormone 42
Insulin 43
Growth hormone 48
The ¡ncretins 50
Multiple choice questions 5
Further reading 52
4
The nature of inflammation and mediators of inflammation
53
Hypersensitivity
54
Mechanisms and chemical mediators of the inflammatory response
57
The
interferons
62
Multiple choice questions
71
Further reading
73
5
Autoimmunity and autoimmune diseases 75
Autoimmunity
75
Immunological tolerance
79
Low-level autoimmunity
80
Triggers and mechanisms of autoimmune reactions
80
Some cellular mechanisms implicated in loss of self-tolerance
and onset and maintenance of autoimmune states
83
Transplant rejection
84
Multiple choice questions
85
Further reading
86
6
Treatment of rheumatoid arthritis and other inflammatory
disorders with biological drugs
89
Rheumatoid arthritis
90
Administration of biological drugs
94
Psoriasis
97
Systemic lupus erythematosus
99
Crohn s disease
100
Multiple choice questions
101
Reference
102
Further reading
102
7
Development of biological antineoplastic drugs
103
Mechanisms and targets for biological antineoplastic drugs
104
Some biological antineoplastic drugs currently in use or development
108
Effectiveness of the biological treatments for cancer
109
Contents
I
ix
Multiple
choice questions
112
Further reading
113
Stem cell therapy
115
The nature of stem cells
115
Embryonic stem cell cultures
117
Preparation of stem cells from the blastocyst
117
Prospeas and the future for regenerative medicine
119
References
121
Further reading
121
Answers to multiple choice questions
123
Glossary
125
Index
135
|
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| edition | 1. publ. |
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| id | DE-604.BV039929215 |
| illustrated | Illustrated |
| indexdate | 2024-12-20T16:05:31Z |
| institution | BVB |
| isbn | 9780853698432 0853698430 9783769254624 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-024787520 |
| oclc_num | 785833493 |
| open_access_boolean | |
| owner | DE-355 DE-BY-UBR DE-19 DE-BY-UBM |
| owner_facet | DE-355 DE-BY-UBR DE-19 DE-BY-UBM |
| physical | XII, 138 S. Ill., graph. Darst. |
| publishDate | 2011 |
| publishDateSearch | 2011 |
| publishDateSort | 2011 |
| publisher | Pharmaceutical Press |
| record_format | marc |
| spellingShingle | Greenstein, Ben 1941- Brook, Daniel A. Biological therapeutics Molekularbiologie (DE-588)4039983-7 gnd Arzneimittelentwicklung (DE-588)4143176-5 gnd |
| subject_GND | (DE-588)4039983-7 (DE-588)4143176-5 |
| title | Biological therapeutics |
| title_auth | Biological therapeutics |
| title_exact_search | Biological therapeutics |
| title_full | Biological therapeutics Ben Greenstein ; Daniel A. Brook |
| title_fullStr | Biological therapeutics Ben Greenstein ; Daniel A. Brook |
| title_full_unstemmed | Biological therapeutics Ben Greenstein ; Daniel A. Brook |
| title_short | Biological therapeutics |
| title_sort | biological therapeutics |
| topic | Molekularbiologie (DE-588)4039983-7 gnd Arzneimittelentwicklung (DE-588)4143176-5 gnd |
| topic_facet | Molekularbiologie Arzneimittelentwicklung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=024787520&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT greensteinben biologicaltherapeutics AT brookdaniela biologicaltherapeutics |