Genetische Analyse komplexer Erkrankungen: Typ-2-Diabetes:
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| Main Author: | |
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| Format: | Thesis/Dissertation Book |
| Language: | German English |
| Published: |
2009
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| Subjects: | |
| Links: | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=017598045&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| Item Description: | Beitr. teilw. dt., teilw. engl. - Enth. 10 Sonderabdr. aus verschiedenen Zeitschr. |
| Physical Description: | 66, [58] Bl. Ill., graph. Darst. 30 cm |
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Record in the Search Index
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| adam_text | Titel: Genetische Analyse komplexer Erkrankungen: Typ-2-Diabetes
Autor: Kovács, Peter
Jahr: 2009
Inhatsverzeichnis
1. Einleitung in die Thematik: genetische Aspekte des Typ-2-Diabetes 4
2. Experimentelle Ansätze in genetischen Analysen komplexer Erkrankungen... 5
3. Genomweite Analysen 6
3.1. Typ-2-Diabetes und genomweite Studien 9
3.2. Positionelle Kandidatengene 11
3.2.1. Transkriptionsfaktor 7-like 2 (TCF7L2) 11
4. Physiologische Kandidatengene 13
4.1. Visfatin 14
4.2. Transkriptionsfaktor forkhead box O1A (FOXO1A) 17
5. Kombinieren von zwei Strategien: physiologische
Kandidatengene + positionelle Strategie 18
5.1. Ectonucleotidepyrophosphatase/phosphodiesterase-1 (ENPP1) 19
5.2. Serum Retinol Binding Protein 4 (RBP4) 21
6. Genetisch isolierte Populationen (Isolatpopulationen) 22
6.1. Positionelle Kandidatengene in Pima Indianern Arizonas 23
6.1.1. Leukemia-Associated Rho Guanine nucleotide exchange factor (LARG) 24
6.1.2. Fettsäuresynthase (Fatty acid synthase - FAS) 26
6.2. Physiologische Kandidatengene in Pima Indianern 28
6.2.1. Insulin Rezeptor Substrat-1 (IRS1) 28
6.2.2. Uncoupling protein-2 (UCP2) 30
7. Diskussion und Ausblick 31
8. Literaturverzeichnis 43
9. Anlagen 56
9.1. Anlage 1 56
9.2. Anlage 2 57
9.3. Anlage 3 60
9.4. Anlage 4 66
3
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| any_adam_object | 1 |
| author | Kovács, Peter 1970- |
| author_GND | (DE-588)120953390 |
| author_facet | Kovács, Peter 1970- |
| author_role | aut |
| author_sort | Kovács, Peter 1970- |
| author_variant | p k pk |
| building | Verbundindex |
| bvnumber | BV035542005 |
| ctrlnum | (OCoLC)320541784 (DE-599)DNB993031439 |
| dewey-full | 616.4 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
| dewey-raw | 616.4 |
| dewey-search | 616.4 |
| dewey-sort | 3616.4 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| format | Thesis Book |
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| illustrated | Illustrated |
| indexdate | 2024-12-20T13:37:26Z |
| institution | BVB |
| language | German English |
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| spellingShingle | Kovács, Peter 1970- Genetische Analyse komplexer Erkrankungen: Typ-2-Diabetes |
| subject_GND | (DE-588)4113937-9 |
| title | Genetische Analyse komplexer Erkrankungen: Typ-2-Diabetes |
| title_auth | Genetische Analyse komplexer Erkrankungen: Typ-2-Diabetes |
| title_exact_search | Genetische Analyse komplexer Erkrankungen: Typ-2-Diabetes |
| title_full | Genetische Analyse komplexer Erkrankungen: Typ-2-Diabetes vorgelegt von Peter Kovacs |
| title_fullStr | Genetische Analyse komplexer Erkrankungen: Typ-2-Diabetes vorgelegt von Peter Kovacs |
| title_full_unstemmed | Genetische Analyse komplexer Erkrankungen: Typ-2-Diabetes vorgelegt von Peter Kovacs |
| title_short | Genetische Analyse komplexer Erkrankungen: Typ-2-Diabetes |
| title_sort | genetische analyse komplexer erkrankungen typ 2 diabetes |
| topic_facet | Hochschulschrift |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=017598045&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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