Verfügbarkeit: Leading pharmaceutical innovation | Technische Universität München

Leading pharmaceutical innovation: trends and drivers for growth in the pharmaceutical industry

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Bibliographische Detailangaben
Beteiligte Personen:	Gassmann, Oliver (VerfasserIn), Reepmeyer, Gerrit (VerfasserIn), Zedtwitz, Maximilian von 1969- (VerfasserIn)
Format:	Buch
Sprache:	Englisch
Veröffentlicht:	Berlin [u.a.] Springer 2008
Ausgabe:	2. ed.
Schlagwörter:	Innovationswettbewerb Pharmazeutische Industrie Marktentwicklung Erfolgsfaktor Arzneimittelmarkt Innovationsmanagement
Links:	http://deposit.dnb.de/cgi-bin/dokserv?id=3077740&prov=M&dok_var=1&dok_ext=htm http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016403380&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
Umfang:	XV, 186 S. graph. Darst., Kt.
ISBN:	9783540776352 3540776354

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Datensatz im Suchindex

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adam_text	OLIVER GASSMANN * GERRIT REEPMEYER MAXIMILIAN VON ZEDTWITZ LEADING PHARMACEUTICAL INNOVATION TRENDS AND DRIVERS FOR GROWTH IN THE PHARMACEUTICAL INDUSTRY SECOND EDITION 4Y SPRINGER CONTENTS I. INNOVATION: KEY TO SUCCESS IN THE PHARMACEUTICAL INDUSTRY 1 THE PRODUCTIVITY PARADOX 1 THE BLOCKBUSTER IMPERATIVE 4 HIGH RISKS IN DRUG DEVELOPMENT 10 STRATEGIES FOR GROWTH 12 DIFFERENTIATION VIA CLINICAL PROFILES , ..; 15 ENTERING THE MARKET QUICKLY 16 CONCLUSIONS 17 II. THE INDUSTRY CHALLENGE: DO YOU REALLY WANT TO BE IN THIS BUSINESS? 19 HIGH COMPLEXITY OF THE INDUSTRY 19 HOW ATTRACTIVE IS THE PHARMACEUTICAL INDUSTRY? 22 FORCE 1: BARGAINING POWER OF SUPPLIERS 24 FORCE 2: BARGAINING POWER OF BUYERS 25 FORCE 3: RISK OF ENTRY FROM POTENTIAL COMPETITORS 26 FORCE 4: THREAT OF SUBSTITUTE PRODUCTS 27 FORCE 5: RIVALRY AMONG ESTABLISHED COMPANIES 28 FORCE 6: THE REGULATORS :. . 28 CONCLUSIONS 30 III. THE SCIENCE AND TECHNOLOGY CHALLENGE: HOW TO FIND NEW DRUGS 33 RISE OF THE BIOTECHNOLOGY INDUSTRY: BOOSTING INNOVATION 33 HIGH-THROUGHPUT SCREENING: FAIL EARLIER, SUCCEED SOONER 38 COMBINATORIAL CHEMISTRY: CUT EXPERIMENTAL CYCLE TIMES 39 BIOINFORMATICS: MORE THAN 100 GIGABYTES OF DATA PER DAY 40 PROTEOMICS: PROFITING FROM THE HUMAN GENOME PROJECT 42 GENOMICS: TOWARDS INDIVIDUALIZATION AND MASS CUSTOMIZATION ....43 PHARMACOGENOMICS: CREATE TAILOR-MADE DRUGS 45 MOLECULAR DESIGN: FROM EXPERIMENTING TO ANALYTIC DESIGN 47 CONCLUSIONS 48 XIV CONTENTS IV. THE PIPELINE MANAGEMENT CHALLENGE: HOW TO ORGANIZE INNOVATION 51 THE RELEVANCE OF PIPELINE MANAGEMENT 51 COMPLEXITY AND PHASES OF THE R&D PROCESS 56 THE IMPORTANCE OF PROJECT AND PORTFOLIO MANAGEMENT 65 THE DISAGGREGATION OF THE PHARMACEUTICAL VALUE CHAIN 68 IMPACT OF OUTSOURCING ON PHARMACEUTICAL R&D 71 RISING IMPORTANCE OF R&D COLLABORATIONS 75 RESEARCH ALLIANCES: ACCESSING EARLY-STAGE INNOVATION 78 IN-LICENSING: ENHANCING THE INNOVATION PIPELINE 1 : 81 CO-DEVELOPMENT: MUTUALLY BENEFITING FROM JOINT RESOURCES, 83 OUT-LICENSING: COMMERCIALIZING INTERNAL RESEARCH RESULTS 86 HOW TO COMMERCIALIZE A BREAKTHROUGH TECHNOLOGY 95 CONCLUSIONS 100 V. THE INTERNATIONALIZATION CHALLENGE: WHERE TO GET ACCESS TO INNOVATION 103 TRENDS AND DRIVERS OF R&D INTERNATIONALIZATION 103 PRIMARY LOCATIONS OF PHARMACEUTICAL R&D AROUND THE WORLD 108 NEW OPPORTUNITIES FOR DRUG DEVELOPMENT IN CHINA....,- 111 THREE PRINCIPAL PROBLEMS OF DISPERSED R&D 117 CONCLUSIONS 121 VI. MANAGEMENT ANSWERS TO PHARMACEUTICAL R&D CHALLENGES ...123 MANAGING R&D ORGANIZATION AT ROCHE 123 MANAGING R&D STRATEGY AT SCHERING 125 MANAGING THE RESEARCH-TO-DEVELOPMENT HANDOVER AT ROCHE 127 MANAGING OUTSOURCING ACTIVITIES AT SOLVIAS.. 130 MANAGING INTELLECTUAL PROPERTY RIGHTS AT BAYER 133 MANAGING OUT-LICENSING ATNOVARTIS 137 MANAGING UNCERTAINTY AT ROCHE 144 MANAGING GLOBAL R&D AT MAJOR SWISS PHARMA COMPANIES 145 MANAGING A NICHE-MARKET STRATEGY AT INTARCIA 151 MANAGING VIRTUAL PROJECT MANAGEMENT POOLS AT ROCHE 153 CONCLUSIONS , ., .....156 VII. FUTURE DIRECTIONS AND TRENDS . *. 159 CONTENTS XV BIBLIOGRAPHY 165 INDEX 173 GLOSSARY . 179 AUTHORS 185
any_adam_object	1
author	Gassmann, Oliver Reepmeyer, Gerrit Zedtwitz, Maximilian von 1969-
author_GND	(DE-588)120671417
author_facet	Gassmann, Oliver Reepmeyer, Gerrit Zedtwitz, Maximilian von 1969-
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dewey-ones	338 - Production
dewey-raw	338.476151
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dewey-tens	330 - Economics
discipline	Wirtschaftswissenschaften
edition	2. ed.
format	Book
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illustrated	Illustrated
indexdate	2024-12-20T13:10:53Z
institution	BVB
isbn	9783540776352 3540776354
language	English
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physical	XV, 186 S. graph. Darst., Kt.
publishDate	2008
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spellingShingle	Gassmann, Oliver Reepmeyer, Gerrit Zedtwitz, Maximilian von 1969- Leading pharmaceutical innovation trends and drivers for growth in the pharmaceutical industry Innovationswettbewerb (DE-588)4192032-6 gnd Pharmazeutische Industrie (DE-588)4045696-1 gnd Marktentwicklung (DE-588)4123713-4 gnd Erfolgsfaktor (DE-588)4197034-2 gnd Arzneimittelmarkt (DE-588)4003131-7 gnd Innovationsmanagement (DE-588)4161817-8 gnd
subject_GND	(DE-588)4192032-6 (DE-588)4045696-1 (DE-588)4123713-4 (DE-588)4197034-2 (DE-588)4003131-7 (DE-588)4161817-8
title	Leading pharmaceutical innovation trends and drivers for growth in the pharmaceutical industry
title_auth	Leading pharmaceutical innovation trends and drivers for growth in the pharmaceutical industry
title_exact_search	Leading pharmaceutical innovation trends and drivers for growth in the pharmaceutical industry
title_full	Leading pharmaceutical innovation trends and drivers for growth in the pharmaceutical industry Oliver Gassmann ; Gerrit Reepmeyer ; Maximilian von Zedtwitz
title_fullStr	Leading pharmaceutical innovation trends and drivers for growth in the pharmaceutical industry Oliver Gassmann ; Gerrit Reepmeyer ; Maximilian von Zedtwitz
title_full_unstemmed	Leading pharmaceutical innovation trends and drivers for growth in the pharmaceutical industry Oliver Gassmann ; Gerrit Reepmeyer ; Maximilian von Zedtwitz
title_short	Leading pharmaceutical innovation
title_sort	leading pharmaceutical innovation trends and drivers for growth in the pharmaceutical industry
title_sub	trends and drivers for growth in the pharmaceutical industry
topic	Innovationswettbewerb (DE-588)4192032-6 gnd Pharmazeutische Industrie (DE-588)4045696-1 gnd Marktentwicklung (DE-588)4123713-4 gnd Erfolgsfaktor (DE-588)4197034-2 gnd Arzneimittelmarkt (DE-588)4003131-7 gnd Innovationsmanagement (DE-588)4161817-8 gnd
topic_facet	Innovationswettbewerb Pharmazeutische Industrie Marktentwicklung Erfolgsfaktor Arzneimittelmarkt Innovationsmanagement
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