Suchergebnisse - Huang, Jingang

Evaluation of the efficacy of the tyrosine kinase inhibitor Nintedanib and characterization of the role of the tyrosine-phosphatase SHP2 in preclinical models of Systemic Sclerosis: = Evaluation der Wirksamkeit des Tyrosinkinase-Inhibitors Nintedanib und Charakterisierung der Rolle der Tyrosinphosphatase SHP2 in präklinischen Modellen der systemischen Sklerose

Activating transcription factor 3 regulates canonical TGFβ signalling in systemic sclerosis

Activation of liver X receptors inhibits experimental fibrosis by interfering with interleukin-6 release from macrophages

Inactivation of tankyrases reduces experimental fibrosis by inhibiting canonical Wnt signalling

TGFβ promotes fibrosis by MYST1-dependent epigenetic regulation of autophagy

Sirt1 regulates canonical TGF-β signalling to control fibroblast activation and tissue fibrosis

Vitamin D receptor regulates TGF-β signalling in systemic sclerosis

Stimulation of the soluble guanylate cyclase (sGC) inhibits fibrosis by blocking non-canonical TGFβ signalling

Nintedanib inhibits fibroblast activation and ameliorates fibrosis in preclinical models of systemic sclerosis

Combined inhibition of morphogen pathways demonstrates additive antifibrotic effects and improved tolerability

Inhibition of H3K27 histone trimethylation activates fibroblasts and induces fibrosis